Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | CCNK | O75909 | 4/20 | 0.37 |
| ▸ | CDK9 | P50750 | 4/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.36 |
| ▸ | PTGES | O14684 | 4/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16498013 | 0.89 | CCNK (0.44) | FFAR2NPC1RAB9ATYRCCNK | |
| SCHEMBL16498184 | 0.85 | FFAR2 (0.43) | FFAR2NPC1RAB9ATYRCCNK | |
| SCHEMBL16498186 | 0.85 | FFAR2 (0.43) | FFAR2NPC1RAB9ATYRCCNK | |
| SCHEMBL1915656 | 0.84 | FFAR2 (0.48) | FFAR2NPC1RAB9ATYRCCNK | |
| SCHEMBL16498356 | 0.77 | CCNK (0.45) | NPC1RAB9ATYRCCNKCDK9 | |
| SCHEMBL1915236 | 0.76 | NPC1 (0.47) | FFAR2NPC1RAB9ATYRCCNK | |
| SCHEMBL1915663 | 0.76 | AR (0.43) | FFAR2NPC1RAB9ACCNKCDK9 | |
| SCHEMBL16498003 | 0.73 | NPC1 (0.46) | NPC1RAB9ATYRCCNKCDK9 | |
| SCHEMBL16498495 | 0.72 | RAB9A (0.46) | NPC1RAB9ATYRCCNKCDK9 | |
| SCHEMBL1915580 | 0.72 | CYP19A1 (0.49) | FFAR2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151434-A1 | NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS | EUROSCREEN S.A. (BE) | 2011-12-08 | — | — | WO | disclosed |