Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29090398 | 0.80 | RPS6KA5 (0.31) | KDM4E | |
| SCHEMBL16512389 | 0.80 | BCAT1 (0.38) | MAPTGSK3AGSK3BGRM1KDM4A | |
| SCHEMBL30881429 | 0.70 | CCNA2 (0.47) | MAPTGSK3AGSK3BALDH1A1KDM4E | |
| SCHEMBL342903 | 0.68 | ADORA3 (0.49) | MAPTESR2ALDH1A1KDM4EHPGD | |
| SCHEMBL2546778 | 0.68 | KHK (0.54) | MAPTGSK3AGSK3BALDH1A1KDM4E | |
| SCHEMBL16498506 | 0.67 | SRC (0.42) | MAPTESR2ALDH1A1KDM4EHPGD | |
| SCHEMBL343580 | 0.66 | KDM4E (0.56) | MAPTGRM1GRM5ALDH1A1KDM4E | |
| SCHEMBL16499060 | 0.65 | KDM4E (0.38) | MAPTESR2ALDH1A1KDM4EHPGD | |
| SCHEMBL17112172 | 0.65 | EGFR (0.43) | MAPTALDH1A1KDM4EHPGDHTT | |
| SCHEMBL22057635 | 0.64 | MAPK1 (0.54) | MAPTGRM1GRM5ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011153588-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2011-12-15 | — | — | WO | disclosed |
| WO-2011153588-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2011-12-15 | — | — | WO | disclosed |