Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 5/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22732689 | 0.81 | GABRA5 (0.44) | KDM4EGABRA5GBA1LSSMAPT | |
| SCHEMBL256028 | 0.80 | PIK3CD (0.43) | KDM4EGABRA5ALDH1A1GBA1LSS | |
| SCHEMBL20006272 | 0.79 | KDM4E (0.39) | KDM4EGABRA5GBA1LSS | |
| SCHEMBL456392 | 0.78 | KDM4E (0.46) | KDM4EGABRA5GBA1LMNALSS | |
| SCHEMBL9082771 | 0.77 | KDM4E (0.43) | KDM4EGABRA5ALDH1A1GBA1LSS | |
| SCHEMBL18810072 | 0.77 | KDM4E (0.49) | KDM4EALDH1A1LMNAPTGESAPP | |
| SCHEMBL3104534 | 0.77 | KDM4E (0.44) | KDM4EGABRA5GBA1LMNAMAPT | |
| SCHEMBL10154541 | 0.77 | GABRA5 (0.42) | KDM4EGABRA5ALDH1A1GBA1ATM | |
| SCHEMBL20745192 | 0.76 | PIK3CD (0.40) | KDM4EGABRA5ALDH1A1GBA1LSS | |
| SCHEMBL18229345 | 0.76 | PIK3CD (0.40) | KDM4EGABRA5ALDH1A1GBA1LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151434-A1 | NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS | EUROSCREEN S.A. (BE) | 2011-12-08 | — | — | WO | disclosed |