Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 3/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | YAP1 | P46937 | 3/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16512122 | 0.92 | OPRD1 (0.44) | OPRD1OPRK1TACR1YAP1TSHR | |
| SCHEMBL16511721 | 0.89 | OPRD1 (0.45) | OPRD1OPRK1TACR1TSHRALOX15 | |
| SCHEMBL12801209 | 0.88 | OPRD1 (0.47) | OPRD1OPRK1TACR1YAP1TLR9 | |
| SCHEMBL16499578 | 0.88 | OPRD1 (0.45) | OPRD1OPRK1TACR1TSHRALOX15 | |
| SCHEMBL12800403 | 0.87 | OPRD1 (0.46) | OPRD1OPRK1TACR1YAP1TLR9 | |
| SCHEMBL1671810 | 0.85 | OPRD1 (0.51) | OPRD1OPRK1TACR1YAP1TLR9 | |
| SCHEMBL1669177 | 0.85 | OPRD1 (0.52) | OPRD1OPRK1TACR1YAP1TLR9 | |
| SCHEMBL1669343 | 0.81 | OPRD1 (0.40) | OPRD1OPRK1TACR1YAP1 | |
| SCHEMBL1668912 | 0.81 | OPRD1 (0.51) | OPRD1OPRK1TACR1YAP1TLR9 | |
| SCHEMBL12800828 | 0.80 | OPRD1 (0.39) | OPRD1OPRK1TACR1YAP1TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011154678-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2011-12-15 | — | — | WO | disclosed |