Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 5/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | POLA1 | P09884 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16499551 | 0.84 | MEN1 (0.33) | SOD1ALDH1A1MEN1KMT2AALOX15 | |
| SCHEMBL16499548 | 0.82 | MAPK1 (0.33) | SOD1ALDH1A1ALOX15POLA1 | |
| Hypargenin C SCHEMBL13532268 | 0.76 | SOD1 (0.55) | SOD1FDPSGGPS1ALDH1A1MEN1 | |
| Hypargenin C SCHEMBL18290364 | 0.76 | SOD1 (0.55) | SOD1FDPSGGPS1ALDH1A1MEN1 | |
| Hypargenin C SCHEMBL31083234 | 0.76 | SOD1 (0.55) | SOD1FDPSGGPS1ALDH1A1MEN1 | |
| SCHEMBL12827353 | 0.76 | OPRD1 (0.46) | ALDH1A1MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL16499412 | 0.76 | OPRD1 (0.46) | ALDH1A1MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL16499555 | 0.76 | OPRD1 (0.46) | ALDH1A1MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL12825563 | 0.76 | OPRD1 (0.46) | ALDH1A1MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL12821421 | 0.74 | SOD1 (0.34) | SOD1EP300USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011155983-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC. (US) | 2011-12-15 | — | — | WO | disclosed |