Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 15/20 | 0.42 |
| ▸ | CTSL | P07711 | 13/20 | 0.42 |
| ▸ | CTSB | P07858 | 12/20 | 0.42 |
| ▸ | CTSK | P43235 | 9/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5521161 | 0.81 | CTSS (0.44) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2822337 | 0.74 | CTSS (0.72) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2819138 | 0.74 | CTSS (0.72) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2819137 | 0.74 | CTSS (0.72) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2816725 | 0.74 | CTSL (0.51) | CTSSCTSLCTSBCTSK | |
| SCHEMBL13791953 | 0.74 | CTSL (0.51) | CTSSCTSLCTSBCTSK | |
| SCHEMBL1273151 | 0.71 | CTSS (0.48) | CTSSCTSLCTSBCTSK | |
| SCHEMBL1273150 | 0.71 | CTSS (0.48) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2820734 | 0.71 | CTSS (0.74) | CTSSCTSLCTSBCTSK | |
| SCHEMBL1272760 | 0.71 | CTSS (0.74) | CTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663958-B1 | HALOALKYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | VIROBAY INC (US) | 2015-02-25 | — | — | EP | claimed |