Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31036065 | 1.00 | MEN1 (0.68) | MEN1KMT2ATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL16384294 | 1.00 | MEN1 (0.68) | MEN1KMT2ATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL4547630 | 0.98 | MEN1 (0.71) | MEN1KMT2ATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL3821431 | 0.92 | TSHR (0.70) | MEN1KMT2ATSHRALDH1A1RECQL | |
| SCHEMBL11758762 | 0.85 | MEN1 (0.94) | MEN1KMT2AALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL21765846 | 0.85 | MEN1 (0.94) | MEN1KMT2AALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL9259257 | 0.85 | MEN1 (0.94) | MEN1KMT2AALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL26553980 | 0.85 | CASP2 (0.69) | MEN1KMT2ATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL22856469 | 0.84 | MEN1 (0.68) | MEN1KMT2ATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL22525938 | 0.84 | MEN1 (0.57) | MEN1KMT2ATSHRALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091985-A1 | COMPOUNDS TARGETING PMP22 FOR THE TREATMENT OF CHARCOT-MARIE-TOOTH DISEASE | DTX PHARMA, INC. (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2021086069-A1 | COMPOUND COMPRISING EZH2 INHIBITOR AND E3 LIGASE BINDER AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING EZH2-ASSOCIATED DISEASE COMPRISING SAME AS ACTIVE INGREDIENT | 재단법인 대구경북첨단의료산업진흥재단 | 2021-05-06 | — | — | WO | disclosed |
| EP-0710667-B1 | Modified oligonucleotides, their preparation and their use | ROCHE DIAGNOSTICS GMBH (DE) | 2011-12-14 | — | — | EP | disclosed |