Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17471720 | 0.79 | CYP4A11 (0.41) | IGF1RALOX15 | |
| SCHEMBL19559097 | 0.79 | TAAR1 (0.45) | IGF1RALOX15 | |
| SCHEMBL257868 | 0.78 | HTR2A (0.52) | HTR2AIGF1RALOX15MAOBNOS3 | |
| SCHEMBL17471702 | 0.78 | BCHE (0.42) | IGF1RALOX15 | |
| SCHEMBL17471707 | 0.77 | CYP1A2 (0.53) | — | |
| SCHEMBL14593527 | 0.76 | S1PR1 (0.42) | NOS3NOS1 | |
| SCHEMBL17471728 | 0.76 | BCHE (0.44) | IGF1RALOX15 | |
| SCHEMBL24620667 | 0.76 | S1PR1 (0.41) | — | |
| SCHEMBL14268146 | 0.76 | CNR1 (0.45) | — | |
| SCHEMBL10830903 | 0.75 | S1PR1 (0.40) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119718-B1 | MACROCYCLIC COMPOUND | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2012-04-11 | — | — | EP | disclosed |