Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 12/20 | 0.38 |
| ▸ | HTR7 | P34969 | 9/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 3/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | PLG | P00747 | 2/20 | 0.36 |
| ▸ | PLAT | P00750 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 3/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | HPN | P05981 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915987 | 0.86 | SLC9A1 (0.52) | SLC9A1HTR2BHTR7DRD2ADRA1D | |
| SCHEMBL16503483 | 0.79 | IRAK4 (0.45) | SLC9A1PLAUCYP3A4CYP2C19 | |
| SCHEMBL7919834 | 0.77 | SLC9A1 (0.56) | SLC9A1HTR2BHTR7DRD2ADRA1D | |
| SCHEMBL7917567 | 0.77 | SLC9A1 (0.50) | SLC9A1HTR2BHTR7DRD2ADRA1D | |
| SCHEMBL7915823 | 0.75 | PLA2G2D (0.50) | — | |
| SCHEMBL16502803 | 0.75 | HTR2B (0.51) | SLC9A1HTR2BHTR7DRD2ADRA1D | |
| SCHEMBL16502736 | 0.73 | HTR5A (0.60) | SLC9A1HTR2BHTR7DRD2ADRA1D | |
| SCHEMBL7919066 | 0.73 | SLC9A1 (0.57) | SLC9A1HTR2BHTR7DRD2ADRA1D | |
| SCHEMBL16502777 | 0.73 | HTR2B (0.53) | SLC9A1HTR2BHTR7DRD2ADRA1D | |
| SCHEMBL16502794 | 0.72 | SLC9A1 (0.45) | SLC9A1HTR2BHTR7DRD2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394987-A1 | ACYLGUANIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2011-12-14 | — | — | EP | disclosed |