Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.52 |
| ▸ | GHSR | Q92847 | 1/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | CTSC | P53634 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | CASP4 | P49662 | 1/20 | 0.48 |
| ▸ | CASP5 | P51878 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | CASP9 | P55211 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.48 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.48 |
| ▸ | IL1RN | P18510 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4375898 | 0.91 | ERBB2 (0.55) | ERAP2ERBB2MMP2MMP9MMP8 | |
| SCHEMBL1650372 | 0.86 | ERAP2 (0.51) | ERAP2GHSRERBB2MMP2MMP9 | |
| SCHEMBL16468642 | 0.86 | CTSC (0.66) | ERAP2MMP2MMP9MMP8MMP1 | |
| SCHEMBL3187724 | 0.85 | ERAP2 (0.55) | ERAP2MMP2MMP9MMP8MMP1 | |
| SCHEMBL3187737 | 0.85 | ERAP2 (0.55) | ERAP2MMP2MMP9MMP8MMP1 | |
| SCHEMBL30988893 | 0.85 | ACE (0.61) | ERAP2GHSRACEMAGI3ECE1 | |
| SCHEMBL2183811 | 0.83 | CTSC (0.70) | ERAP2CTSCMAGI3CCKBRECE1 | |
| SCHEMBL2193237 | 0.83 | GHSR (0.61) | GHSRMMP2MMP9MMP8MMP1 | |
| SCHEMBL30799670 | 0.82 | GHSR (0.68) | ERAP2GHSRMMP9MMP8MMP1 | |
| SCHEMBL2191649 | 0.82 | ERAP2 (0.53) | ERAP2GHSRMMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985402-B2 | Ultrasound contrast agent of peptide monomers; peptide vectors having high KDR binding affinity; gas filled microvesicle containing a fluorinated gas and a phospholipid | BRACCO SUISSE SA (CH) | 2011-07-26 | — | — | US | disclosed |
| US-20080152594-A1 | TARGETING VECTOR-PHOSPHOLIPID CONJUGATES | BRACCO SUISSE SA (CH) | 2008-06-26 | — | — | US | disclosed |