SCHEMBL16504635

SCHEMBL16504635

C/C=C(\C)C(=O)Oc1ccc(OC(=O)/C(C)=C/C)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.46
ELANE P08246 5/20 0.43
RAB9A P51151 2/20 0.43
KMT2A Q03164 6/20 0.42
MAPT P10636 5/20 0.42
MEN1 O00255 3/20 0.42
POLB P06746 1/20 0.42
PKM P14618 1/20 0.42
KDM4E B2RXH2 1/20 0.41
TTR P02766 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ATM Q13315 1/20 0.40
HSD17B10 Q99714 2/20 0.39
ALDH1A1 P00352 2/20 0.39
HTT P42858 1/20 0.39
HSP90AA1 P07900 1/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28914529 0.92 GSK3B (0.48) LMNARAB9AKMT2AMAPTMEN1
SCHEMBL3120830 0.92 GSK3B (0.48) LMNARAB9AKMT2AMAPTMEN1
SCHEMBL27768540 0.92 LMNA (0.61) LMNAELANEKMT2AMAPTALDH1A1
SCHEMBL7457988 0.92 ELANE (0.44) LMNAELANEKMT2AMAPTMEN1
SCHEMBL215942 0.92 ELANE (0.44) LMNAELANEKMT2AMAPTMEN1
SCHEMBL4473693 0.90 KMT2A (0.41) LMNAELANEKMT2AMAPTMEN1
SCHEMBL28496913 0.90 CYP11B1 (0.46) LMNAELANEKMT2AMAPTMEN1
SCHEMBL809326 0.89 ELANE (0.47) ELANEKMT2AMAPTKDM4EATM
SCHEMBL4324963 0.89 ELANE (0.47) ELANEKMT2AMAPTKDM4EATM
SCHEMBL165007 0.89 ELANE (0.47) ELANEKMT2AMAPTKDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11168165-B2 Controlled radical polymerization in water-in-water dispersion RHODIA OPERATIONS (FR) 2021-11-09 US disclosed
US-20190085110-A1 Controlled radical polymerization in water-in-water dispersion SPECIALTY OPERATIONS FRANCE (FR) 2019-03-21 US disclosed
US-10160821-B2 Controlled radical polymerization in water-in-water dispersion RHODIA OPERATIONS (FR) 2018-12-25 US disclosed
US-20150057411-A1 Controlled radical polymerization in water-in-water dispersion SPECIALTY OPERATIONS FRANCE (FR) 2015-02-26 US disclosed