SCHEMBL27768540

SCHEMBL27768540

CC=C(C)C(=O)Oc1ccc(C)cc1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.61
KMT2A Q03164 3/20 0.45
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
GSK3B P49841 1/20 0.39
PTK2B Q14289 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
PRSS1 P07477 1/20 0.39
ACR P10323 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MAOB P27338 1/20 0.39
ELANE P08246 1/20 0.39
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16504635 0.92 LMNA (0.46) LMNAKMT2AALDH1A1GAAGSK3B
SCHEMBL14510436 0.85 LMNA (0.57) LMNAKMT2AALDH1A1GAACYP1A2
SCHEMBL7457988 0.84 ELANE (0.44) LMNAKMT2AALDH1A1GAAELANE
SCHEMBL28914529 0.84 GSK3B (0.48) LMNAKMT2AALDH1A1GAACYP1A2
SCHEMBL3120830 0.84 GSK3B (0.48) LMNAKMT2AALDH1A1GAACYP1A2
SCHEMBL215942 0.84 ELANE (0.44) LMNAKMT2AALDH1A1GAAELANE
SCHEMBL28996082 0.83 LMNA (0.55) LMNAKMT2AALDH1A1GAAMAOB
SCHEMBL7064531 0.83 LMNA (0.70) LMNAKMT2AALDH1A1GAACYP1A2
SCHEMBL4473693 0.82 KMT2A (0.41) LMNAKMT2AALDH1A1GAACYP1A2
SCHEMBL28496913 0.82 CYP11B1 (0.46) LMNAKMT2ACYP1A2CYP2C19L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115322100-A Delta, epsilon-alkenyl ketone compound and preparation method and application thereof 南京工业大学 2022-11-11 CN disclosed
CN-110066231-B Aza beta-substituted Morita-Baylis-Hillman type compound and synthetic method thereof 江苏师范大学 2021-06-25 CN disclosed
CN-112646417-A Quantum dot ink, preparation method of quantum dot light-emitting diode and display device 广东聚华印刷显示技术有限公司 2021-04-13 CN disclosed
CN-108291108-B Coating agent 日本曹达株式会社 2020-12-18 CN disclosed
CN-102065795-B Intraocular lens with photosensitizer and method for modifying the refractive index of the lens BAUSCH & LOMB 2014-09-10 CN disclosed
CN-103889368-A Method for changing refractive index of optical material and optical visual device obtained by same BAUSCH & LOMB 2014-06-25 CN disclosed
CN-101489509-B Method for changing refractive index of optical material and optical device BAUSCH & LOMB 2013-03-13 CN disclosed
CN-102065795-A Intraocular lens with photosensitizer and method for modifying the refractive index of the lens BAUSCH & LOMB 2011-05-18 CN disclosed
CN-101489509-A Optical materials and methods for changing refractive index BAUSCH & LOMB (US) 2009-07-22 CN disclosed