SCHEMBL16507845

SCHEMBL16507845

CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)NC)[C@@H](C)O

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 6/20 0.58
▸ NPY5R Q15761 6/20 0.58
▸ NPY1R P25929 5/20 0.58
▸ NPY2R P49146 3/20 0.58
▸ APLNR P35414 1/20 0.56
▸ GLP1R P43220 10/20 0.54
▸ SCTR P47872 1/20 0.54
▸ OPRM1 P35372 1/20 0.54
▸ OPRD1 P41143 1/20 0.54
▸ OPRK1 P41145 1/20 0.54
▸ KISS1R Q969F8 1/20 0.51
▸ GCGR P47871 1/20 0.51
▸ GIPR P48546 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16507752 0.98 NPY5R (0.60) NPY4RNPY5RNPY1RNPY2RAPLNR
SCHEMBL16508056 0.97 GLP1R (0.56) NPY4RNPY5RNPY1RNPY2RAPLNR
SCHEMBL16508039 0.94 GLP1R (0.57) NPY4RNPY5RNPY1RNPY2RAPLNR
SCHEMBL16508000 0.93 NPY5R (0.63) NPY4RNPY5RNPY1RNPY2RAPLNR
SCHEMBL16508004 0.92 NPY5R (0.60) NPY4RNPY5RNPY1RNPY2RAPLNR
SCHEMBL16507891 0.91 NPY4R (0.57) NPY4RNPY5RNPY1RNPY2RAPLNR
SCHEMBL16507836 0.91 NPY5R (0.61) NPY4RNPY5RNPY1RNPY2RGLP1R
SCHEMBL16507874 0.91 NPY5R (0.63) NPY4RNPY5RNPY1RNPY2RAPLNR
SCHEMBL16507994 0.91 NPY5R (0.63) NPY4RNPY5RNPY1RNPY2RAPLNR
SCHEMBL16507753 0.91 NPY4R (0.67) NPY4RNPY5RNPY1RNPY2RAPLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS ANTHOR THERAPEUTICS, INC. 2011-12-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS PTH1R, MC1R, CASR NPY4R 1387/4885NPY5R 1478/4885NPY1R 800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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