SCHEMBL16507891

SCHEMBL16507891

CCCCCCCCCCCCCCCC(=O)NCC(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CO)C(=O)NC

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 9/20 0.57
▸ NPY5R Q15761 8/20 0.57
▸ NPY1R P25929 7/20 0.57
▸ NPY2R P49146 5/20 0.57
▸ APLNR P35414 2/20 0.54
▸ KISS1R Q969F8 1/20 0.52
▸ GLP1R P43220 3/20 0.51
▸ SCTR P47872 1/20 0.51
▸ NMUR2 Q9GZQ4 3/20 0.51
▸ NMUR1 Q9HB89 3/20 0.51
▸ C5AR1 P21730 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16508056 0.95 GLP1R (0.56) NPY4RNPY5RNPY1RNPY2RAPLNR
SCHEMBL16507845 0.91 NPY4R (0.58) NPY4RNPY5RNPY1RNPY2RAPLNR
SCHEMBL16507753 0.91 NPY4R (0.67) NPY4RNPY5RNPY1RNPY2RAPLNR
SCHEMBL16508133 0.91 NPY4R (0.67) NPY4RNPY5RNPY1RNPY2RAPLNR
SCHEMBL16507965 0.90 NPY4R (0.59) NPY4RNPY5RNPY1RNPY2RAPLNR
SCHEMBL10169091 0.90 APLNR (0.48) NPY4RNPY5RNPY1RNPY2RAPLNR
SCHEMBL16507752 0.89 NPY5R (0.60) NPY4RNPY5RNPY1RNPY2RAPLNR
SCHEMBL16507961 0.89 NPY4R (0.70) NPY4RNPY5RNPY1RNPY2R
SCHEMBL16508077 0.89 NPY4R (0.63) NPY4RNPY5RNPY1RNPY2RAPLNR
SCHEMBL16507874 0.88 NPY5R (0.63) NPY4RNPY5RNPY1RNPY2RAPLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS ANTHOR THERAPEUTICS, INC. 2011-12-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS PTH1R, MC1R, CASR NPY4R 1387/4885NPY5R 1478/4885NPY1R 800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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