SCHEMBL16508056

SCHEMBL16508056

CCCCCCCCCCCCCCCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)NC)[C@@H](C)O

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 13/20 0.56
▸ SCTR P47872 1/20 0.56
▸ OPRM1 P35372 1/20 0.55
▸ OPRD1 P41143 1/20 0.55
▸ OPRK1 P41145 1/20 0.55
▸ NPY4R P50391 4/20 0.54
▸ NPY5R Q15761 4/20 0.54
▸ NPY1R P25929 3/20 0.54
▸ NPY2R P49146 1/20 0.54
▸ APLNR P35414 1/20 0.54
▸ GCGR P47871 1/20 0.52
▸ ECE1 P42892 1/20 0.51
▸ MUS81 Q96NY9 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16507845 0.97 NPY4R (0.58) GLP1RSCTROPRM1OPRD1OPRK1
SCHEMBL16507891 0.95 NPY4R (0.57) GLP1RSCTRNPY4RNPY5RNPY1R
SCHEMBL16507752 0.95 NPY5R (0.60) GLP1RSCTROPRM1OPRD1OPRK1
SCHEMBL16508039 0.91 GLP1R (0.57) GLP1RSCTROPRM1OPRD1OPRK1
SCHEMBL16508000 0.90 NPY5R (0.63) GLP1RSCTROPRM1OPRD1OPRK1
SCHEMBL16507945 0.90 APLNR (0.50) GLP1RSCTROPRM1OPRD1OPRK1
SCHEMBL16508004 0.89 NPY5R (0.60) GLP1RSCTROPRM1OPRD1OPRK1
SCHEMBL16507836 0.88 NPY5R (0.61) GLP1RSCTRNPY4RNPY5RNPY1R
SCHEMBL16507994 0.88 NPY5R (0.63) GLP1RSCTRNPY4RNPY5RNPY1R
SCHEMBL16507874 0.88 NPY5R (0.63) GLP1RSCTRNPY4RNPY5RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS ANTHOR THERAPEUTICS, INC. 2011-12-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS PTH1R, MC1R, CASR GLP1R 120/4885SCTR 419/4885OPRM1 1747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback