Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 13/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.51 |
| ▸ | NPY1R | P25929 | 7/20 | 0.51 |
| ▸ | NPY2R | P49146 | 5/20 | 0.51 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.45 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | GIPR | P48546 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16509029 | 1.00 | NPY4R (0.51) | NPY4RNPY5RNPY1RNPY2RPLA2G10 | |
| SCHEMBL16509013 | 0.94 | NPY4R (0.49) | NPY4RNPY5RNPY1RNPY2RGLP1R | |
| SCHEMBL16509065 | 0.93 | NPY4R (0.57) | NPY4RNPY5RNPY1RNPY2RPLA2G10 | |
| SCHEMBL16508989 | 0.92 | NPY4R (0.46) | NPY4RNPY5RNPY1RNPY2RPLA2G10 | |
| SCHEMBL16509117 | 0.92 | NPY4R (0.57) | NPY4RNPY5RNPY1RNPY2RKISS1R | |
| SCHEMBL16509024 | 0.91 | NPY4R (0.56) | NPY4RNPY5RNPY1RNPY2RPLA2G10 | |
| SCHEMBL16508981 | 0.90 | NPY4R (0.45) | NPY4RNPY5RNPY1RNPY2RGLP1R | |
| SCHEMBL16509016 | 0.90 | NPY4R (0.45) | NPY4RNPY5RNPY1RNPY2RGLP1R | |
| SCHEMBL16507975 | 0.90 | NPY4R (0.43) | NPY4RNPY5RNPY1RNPY2RGLP1R | |
| SCHEMBL16509114 | 0.89 | GLP1R (0.48) | GLP1RGCGRGIPRRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110301087-A1 | CRF1 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. | 2011-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301087-A1 | CRF1 RECEPTOR COMPOUNDS | CRHR1, CRH, CRHR2 | NPY4R 109/4885NPY5R 149/4885NPY1R 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.