Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI | P10646 | 1/20 | 0.49 |
| ▸ | NPY4R | P50391 | 5/20 | 0.45 |
| ▸ | NPY1R | P25929 | 4/20 | 0.45 |
| ▸ | NPY2R | P49146 | 4/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | IL23R | Q5VWK5 | 3/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NMT2 | O60551 | 1/20 | 0.43 |
| ▸ | NMT1 | P30419 | 1/20 | 0.43 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16508141 | 0.98 | TFPI (0.49) | TFPINPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL16507930 | 0.96 | TFPI (0.48) | TFPINPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL16508153 | 0.93 | TFPI (0.46) | TFPINPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL16508070 | 0.91 | NPY4R (0.61) | TFPINPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL16508068 | 0.89 | NPY4R (0.61) | TFPINPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL16509011 | 0.89 | NPY5R (0.48) | TFPINPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL16507921 | 0.87 | NPY4R (0.54) | TFPINPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL16508548 | 0.86 | SIRT5 (0.44) | TFPINPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL16507857 | 0.86 | NMT2 (0.46) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL16508045 | 0.85 | TFPI (0.54) | TFPINPY2RIL23RKEAP1KISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110294738-A1 | PTHR1 RECEPTOR COMPOUNDS | ANTHOR THERAPEUTICS, INC. | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294738-A1 | PTHR1 RECEPTOR COMPOUNDS | PTH1R, MC1R, CASR | TFPI 2646/4885NPY4R 1387/4885NPY1R 800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.