SCHEMBL1650831

SCHEMBL1650831

O=C(O)N1C=Cc2ccccc2C1c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.49
ALDH1A1 P00352 4/20 0.41
MAPT P10636 4/20 0.41
BRD4 O60885 1/20 0.38
CCL2 P13500 1/20 0.38
EDNRA P25101 1/20 0.37
HTR1A P08908 1/20 0.36
HTR2A P28223 1/20 0.36
HTR7 P34969 1/20 0.36
HTR6 P50406 1/20 0.36
HDAC4 P56524 5/20 0.35
P2RX4 Q99571 1/20 0.34
MEN1 O00255 2/20 0.34
USP2 O75604 2/20 0.34
HPGD P15428 2/20 0.34
KMT2A Q03164 2/20 0.34
ALOX15 P16050 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
HTT P42858 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8211547 0.83 ATM (0.47) ATMALDH1A1MAPTBRD4CCL2
SCHEMBL14935851 0.77 ATM (0.41) ATMALDH1A1MAPTBRD4CCL2
SCHEMBL8521314 0.75 ATM (0.40) ATMALDH1A1MAPTBRD4CCL2
SCHEMBL3062557 0.74 ATM (0.41) ATMALDH1A1MAPTLMNA
SCHEMBL16469941 0.72 BRD4 (0.37) ATMALDH1A1MAPTBRD4CCL2
SCHEMBL10757217 0.70 ATM (0.43) ATMALDH1A1MAPTBRD4CCL2
SCHEMBL3062426 0.70 ALDH1A1 (0.41) ATMALDH1A1MAPTHPGDKDM4E
SCHEMBL24017022 0.69 ALDH1A1 (0.49) ATMALDH1A1MAPTBRD4CCL2
SCHEMBL3065113 0.69 ALDH1A1 (0.41) ATMALDH1A1MAPTHDAC8HDAC3
SCHEMBL14156129 0.68 ATM (0.47) ATMALDH1A1MAPTBRD4CCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106410031-B Organic solar cell with adjustable incident light intensity and preparation method thereof 上海大学 2020-01-17 CN claimed
CN-105226199-A Be applied to the bielectron implanted layer structure of organic electroluminescence device, be inverted organic electroluminescence device and preparation method thereof UNIV SHANGHAI 2016-01-06 CN claimed
CN-103956434-A Two-sided organic light-emitting device based on OLED modulation and preparation method thereof UNIV SHANGHAI 2014-07-30 CN claimed
CN-103594636-A Organic electroluminescent and laser luminescent device based on double TFT modulation and manufacturing method thereof UNIV SHANGHAI 2014-02-19 CN claimed
WO-2010103529-A1 A NEW METHOD FOR THE PREPARATION OF SOLIFENACIN AND NEW INTERMEDIATE THEREOF MEGAFINE PHARMA(P) LTD. (IN) 2010-09-16 WO claimed
WO-2021044262-A1 LIGHT-EMITTING DEVICE, DISPLAY DEVICE, ELECTRONIC APPLIANCE, ORGANIC COMPOUND, AND ILLUMINATOR 株式会社半導体エネルギー研究所 2021-03-11 WO disclosed
WO-2020229918-A1 LIGHT-EMITTING DEVICE, LIGHT-EMITTING APPARATUS, DISPLAY DEVICE, ELECTRONIC APPARATUS, AND LIGHTING DEVICE 株式会社半導体エネルギー研究所 2020-11-19 WO disclosed
WO-2020183264-A1 LIGHT-EMITTING DEVICE, LIGHT-EMITTING EQUIPMENT, DISPLAY APPARATUS, ELECTRONIC EQUIPMENT, AND LIGHTING APPARATUS 株式会社半導体エネルギー研究所 2020-09-17 WO disclosed
CN-105985775-B Method for preparing rare earth-free fluorescent material and method for photo-induced white light emission by using same 合皓股份有限公司 2018-09-04 CN disclosed
CN-105646367-B Bipolar compound derived from cis-stilbene/fluorene spirochete 彩丰精技股份有限公司 2018-05-22 CN disclosed
CN-106410031-A Organic solar cell with adjustable incident light intensity and preparation method thereof 上海大学 2017-02-15 CN disclosed
CN-102977150-B Transition metal complex structure containing carbene ligand and application thereof in luminescent material 郑建鸿 2016-07-06 CN disclosed
CN-105226199-A Be applied to the bielectron implanted layer structure of organic electroluminescence device, be inverted organic electroluminescence device and preparation method thereof UNIV SHANGHAI 2016-01-06 CN disclosed
CN-103956434-A Two-sided organic light-emitting device based on OLED modulation and preparation method thereof UNIV SHANGHAI 2014-07-30 CN disclosed
CN-103594636-A Organic electroluminescent and laser luminescent device based on double TFT modulation and manufacturing method thereof UNIV SHANGHAI 2014-02-19 CN disclosed
EP-2406257-A1 A NEW METHOD FOR THE PREPARATION OF SOLIFENACIN AND NEW INTERMEDIATE THEREOF Megafine Pharma (P) Ltd. (IN) 2012-01-18 EP disclosed
US-7927613-B2 Pharmaceutical co-crystal compositions UNIVERSITY OF SOUTH FLORIDA (US) 2011-04-19 US disclosed
WO-2010103529-A1 A NEW METHOD FOR THE PREPARATION OF SOLIFENACIN AND NEW INTERMEDIATE THEREOF MEGAFINE PHARMA(P) LTD. (IN) 2010-09-16 WO disclosed
US-7790905-B2 Pharmaceutical propylene glycol solvate compositions MCNEIL-PPC, INC. (US) 2010-09-07 US disclosed