Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CCL2 | P13500 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1650831 | 0.83 | ATM (0.49) | ATMALDH1A1MAPTP2RX4MEN1 | |
| SCHEMBL3062557 | 0.79 | ATM (0.41) | ATMALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL3062426 | 0.75 | ALDH1A1 (0.41) | ATMALDH1A1MAPTSMN1; SMN2GAA | |
| SCHEMBL10756064 | 0.74 | ATM (0.41) | ATMALDH1A1MAPTP2RX4MEN1 | |
| SCHEMBL3223946 | 0.72 | KIF11 (0.40) | ATMALDH1A1P2RX4MEN1KMT2A | |
| SCHEMBL9112803 | 0.71 | ALDH1A1 (0.46) | ATMALDH1A1MAPTP2RX4KMT2A | |
| SCHEMBL6977310 | 0.69 | ATM (0.39) | ATMALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6372301 | 0.68 | ATM (0.46) | ATMALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL24017022 | 0.67 | ALDH1A1 (0.49) | ATMALDH1A1MAPTP2RX4MEN1 | |
| SCHEMBL16469941 | 0.67 | BRD4 (0.37) | ATMALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017927-A | Quinuclidine derivatives and medicinal composition thereof | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |