Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BECN1 | Q14457 | 7/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | GRPR | P30550 | 1/20 | 0.34 |
| ▸ | YWHAZ | P63104 | 1/20 | 0.34 |
| ▸ | RAMP3 | O60896 | 4/20 | 0.34 |
| ▸ | CALCR | P30988 | 4/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.33 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.33 |
| ▸ | TFPI | P10646 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19102245 | 0.93 | BECN1 (0.35) | BECN1OPRK1GRPRYWHAZRAMP3 | |
| SCHEMBL19102244 | 0.87 | BECN1 (0.34) | BECN1OPRK1GRPRYWHAZRAMP3 | |
| SCHEMBL19102241 | 0.86 | GRPR (0.52) | GRPR | |
| SCHEMBL21186302 | 0.77 | GRPR (0.56) | GRPR | |
| SCHEMBL34464906 | 0.77 | NMUR2 (0.47) | BECN1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL2195684 | 0.74 | HDAC3 (0.41) | BECN1OPRK1HDAC3HDAC1HDAC2 | |
| SCHEMBL2196378 | 0.69 | NPY4R (0.42) | BECN1OPRK1HDAC3HDAC1HDAC2 | |
| SCHEMBL29994317 | 0.69 | IL23R (0.52) | GRPR | |
| SCHEMBL10744274 | 0.69 | OPRL1 (0.42) | TFPI | |
| Cibinetide SCHEMBL29367092 | 0.68 | TFPI (0.45) | BECN1RAMP3CALCRNMUR2NMUR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110293517-A1 | Nitrogen-Containing Macrocyclic Conjugates As Radiopharmaceuticals | THE UNIVERSITY OF MELBOURNE (AU) | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110293517-A1 | Nitrogen-Containing Macrocyclic Conjugates As Radiopharmaceuticals | NCL, NUDC, C3AR1 | BECN1 960/4885OPRK1 1931/4885GRPR 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.