Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BECN1 | Q14457 | 11/20 | 0.34 |
| ▸ | YWHAZ | P63104 | 1/20 | 0.33 |
| ▸ | GRPR | P30550 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | RAMP3 | O60896 | 2/20 | 0.31 |
| ▸ | CALCR | P30988 | 2/20 | 0.31 |
| ▸ | TFPI | P10646 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16508351 | 0.87 | BECN1 (0.36) | BECN1YWHAZGRPROPRK1KEAP1 | |
| SCHEMBL19102245 | 0.84 | BECN1 (0.35) | BECN1YWHAZGRPROPRK1KEAP1 | |
| SCHEMBL19102241 | 0.75 | GRPR (0.52) | GRPR | |
| SCHEMBL34464906 | 0.73 | NMUR2 (0.47) | BECN1KEAP1TFPI | |
| SCHEMBL2195684 | 0.71 | HDAC3 (0.41) | BECN1OPRK1KEAP1TFPI | |
| SCHEMBL2196378 | 0.66 | NPY4R (0.42) | BECN1OPRK1KEAP1 | |
| SCHEMBL29994317 | 0.66 | IL23R (0.52) | GRPR | |
| SCHEMBL10744274 | 0.66 | OPRL1 (0.42) | TFPI | |
| SCHEMBL29727699 | 0.64 | OPRL1 (0.43) | BECN1TFPI | |
| Cibinetide SCHEMBL29367092 | 0.64 | TFPI (0.45) | BECN1RAMP3CALCRTFPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701694-B2 | Nitrogen-containing macrocyclic conjugates as radiopharmaceuticals | THE UNIVERSITY OF MELBOURNE (AU) | 2017-07-11 | — | — | US | disclosed |