Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BECN1 | Q14457 | 10/20 | 0.35 |
| ▸ | GRPR | P30550 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | YWHAZ | P63104 | 1/20 | 0.33 |
| ▸ | RAMP3 | O60896 | 2/20 | 0.32 |
| ▸ | CALCR | P30988 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16508351 | 0.93 | BECN1 (0.36) | BECN1GRPROPRK1KEAP1HDAC3 | |
| SCHEMBL19102244 | 0.84 | BECN1 (0.34) | BECN1GRPROPRK1KEAP1YWHAZ | |
| SCHEMBL19102241 | 0.80 | GRPR (0.52) | GRPR | |
| SCHEMBL34464906 | 0.74 | NMUR2 (0.47) | BECN1KEAP1HDAC3HDAC1HDAC2 | |
| SCHEMBL2195684 | 0.72 | HDAC3 (0.41) | BECN1OPRK1KEAP1HDAC3HDAC1 | |
| SCHEMBL21186302 | 0.72 | GRPR (0.56) | GRPR | |
| SCHEMBL2196378 | 0.67 | NPY4R (0.42) | BECN1OPRK1KEAP1HDAC3HDAC1 | |
| SCHEMBL29994317 | 0.67 | IL23R (0.52) | GRPR | |
| SCHEMBL10744274 | 0.67 | OPRL1 (0.42) | — | |
| Cibinetide SCHEMBL29367092 | 0.65 | TFPI (0.45) | BECN1RAMP3CALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701694-B2 | Nitrogen-containing macrocyclic conjugates as radiopharmaceuticals | THE UNIVERSITY OF MELBOURNE (AU) | 2017-07-11 | — | — | US | disclosed |