SCHEMBL16508372

SCHEMBL16508372

CC(C(=O)O)c1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 11/20 0.63
PTGS1 P23219 11/20 0.50
LMNA P02545 5/20 0.50
CYP2C9 P11712 5/20 0.50
CXCR1 P25024 4/20 0.50
CXCR2 P25025 4/20 0.50
AKR1C3 P42330 3/20 0.50
SLC22A6 Q4U2R8 3/20 0.50
TSHR P16473 2/20 0.50
AKR1C2 P52895 2/20 0.50
CXCL8 P10145 2/20 0.50
PMP22 Q01453 2/20 0.50
ALB P02768 1/20 0.50
ESR1 P03372 1/20 0.50
ALOX5 P09917 1/20 0.50
RARB P10826 1/20 0.50
ADRB3 P13945 1/20 0.50
NFKB1 P19838 1/20 0.50
HTR2A P28223 1/20 0.50
NR1I3 Q14994 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27973540 0.89 PTGS2 (0.48) PTGS2LMNACYP2C9TSHRMAPT
SCHEMBL6136346 0.82 PTGS2 (0.56) PTGS2PTGS1LMNACYP2C9CXCR1
SCHEMBL66842 0.81 PTGS2 (0.75) PTGS2PTGS1LMNACYP2C9CXCR1
SCHEMBL3418 0.81 PTGS2 (0.75) PTGS2PTGS1LMNACYP2C9CXCR1
Benzene SCHEMBL28145708 0.81 PTGS2 (0.75) PTGS2PTGS1LMNACYP2C9CXCR1
SCHEMBL23581099 0.81 PTGS2 (0.75) PTGS2PTGS1LMNACYP2C9CXCR1
SCHEMBL10411845 0.81 PTGS2 (0.75) PTGS2PTGS1LMNACYP2C9CXCR1
Iodide SCHEMBL3868944 0.81 PTGS2 (0.75) PTGS2PTGS1LMNACYP2C9CXCR1
SCHEMBL68873 0.81 PTGS2 (0.75) PTGS2PTGS1LMNACYP2C9CXCR1
SCHEMBL59197 0.81 PTGS2 (0.74) PTGS2PTGS1LMNACYP2C9CXCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9859505-B2 Charge-transporting molecular glass mixtures, luminescent molecular glass mixtures, or combinations thereof or organic light emitting diodes and other organic electronics and photonics applications MOLECULAR GLASSES, INC. (US) 2018-01-02 US disclosed
EP-3039487-A1 MOLECULAR GLASS MIXTURES FOR ORGANIC ELECTRONICS APPLICATIONS Molaire Consulting LLC (US) 2016-07-06 EP disclosed
US-20150053894-A1 Charge-transporting Molecular Glass Mixtures, Luminescent Molecular Glass Mixtures, or Combinations Thereof for Organic Light Emitting Diodes and other Organic Electronics and Photonics Applications Molaire Consulting 2015-02-26 US disclosed