Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.75 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | CXCR1 | P25024 | 4/20 | 0.62 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.62 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.62 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | THPO | P40225 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3418 | 1.00 | PTGS2 (0.75) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| Benzene SCHEMBL28145708 | 1.00 | PTGS2 (0.75) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| SCHEMBL10411845 | 1.00 | PTGS2 (0.75) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| SCHEMBL68873 | 1.00 | PTGS2 (0.75) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| Iodide SCHEMBL3868944 | 1.00 | PTGS2 (0.75) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| SCHEMBL23581099 | 1.00 | PTGS2 (0.75) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| Water SCHEMBL5314805 | 0.97 | PTGS2 (0.72) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| SCHEMBL9569033 | 0.97 | PTGS2 (0.72) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| SCHEMBL6534961 | 0.97 | PTGS2 (0.72) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| SCHEMBL11783168 | 0.97 | PTGS2 (0.72) | PTGS2PTGS1LMNACXCR1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 919 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290491-A | Copper nanocluster and preparation method thereof | 清华大学 | 2024-07-05 | — | — | CN | claimed |
| CN-118146112-A | Capsaicin molecule with optical activity and synthesis method and application thereof | 南京理工大学 | 2024-06-07 | — | — | CN | claimed |
| US-11999741-B2 | Process for the synthesis of 6-((3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl)-3-(tetrahydropyran-4-yl-7H-imidazo[1,5-a]pyrazin-8-one | CARDURION PHARMACEUTICALS, INC. (US) | 2024-06-04 | — | — | US | claimed |
| WO-2024040267-A2 | DIRECT SYNTHESIS OF N-(3-SUBSTITUTED-CHROMAN-4-YL)-7H- PYRROLO[2,3-D]PYRIMIDIN-4-AMINES AND DERIVATIVES THEREOF | MITOKININ, INC. (US) | 2024-02-22 | — | — | WO | claimed |
| US-11760750-B1 | Process for preparing levoketoconazole | NURAY CHEMICALS PRIVATE LIMITED (IN) | 2023-09-19 | — | — | US | claimed |
| CN-116727659-A | Chiral copper nanocluster and preparation method thereof | 清华大学 | 2023-09-12 | — | — | CN | claimed |
| CN-114805095-B | Preparation method of (S) -5-methoxy-1, 2,3, 4-tetrahydro-N-propyl-2-naphthylamine | 上海柏狮生物科技有限公司 | 2023-07-21 | — | — | CN | claimed |
| US-20230122169-A1 | NOVEL METHOD FOR PREPARING (-)-CIBENZOLINE SUCCINATE | CELLTRION, INC. (KR) | 2023-04-20 | — | — | US | claimed |
| CN-114805095-A | Preparation method of (S) -5-methoxy-1, 2,3, 4-tetrahydro-N-propyl-2-naphthylamine | 上海柏狮生物科技有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-109295152-B | Method for catalyzing, esterifying and splitting 2-phenylpropionic acid enantiomer by Novozym435 lipase | 湖南理工学院 | 2021-09-07 | — | — | CN | claimed |
| EP-1611111-A2 | PROCESS FOR RESOLVING 2,4-DIAMINO-3,6-DIHYDRO-1,3,5-TRIAZINES, USEFUL FOR THE TREATMENT OF DISORDERS ASSOCIATED WITH INSULIN RESISTANCE SYNDROME | MERCK PATENT GmbH (DE) | 2006-01-04 | — | — | EP | claimed |
| US-20050267104-A1 | E.g., ({[Acetyl({(5R)-3-[4-(1,1-dioxidotetrahydro-2H-thiopyran4-yl)-3-fluorophenyl]-2-oxo-1,3-oxazolidin-5-yl}-methyl)amino]carbonyl}oxymethyl acetate; these compounds have potent activity with excellent oral bioavailability against Gram-positive and Gram-negative bacteria | PHARMACIA & UPJOHN COMPANY LLC | 2005-12-01 | — | — | US | claimed |
| WO-2005090295-A2 | 2-PHENYLPROPIONIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE' PHA.R.MA S.P.A. (IT) | 2005-09-29 | — | — | WO | claimed |
| WO-2005028473-A1 | ACYLOXYMETHYLCARBAMATE PRODRUGS OF OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-03-31 | — | — | WO | claimed |
| EP-1504002-A1 | OPTICALLY ACTIVE &bgr;-AMINOKETONES, OPTICALLY ACTIVE 1,3-AMINOALCOHOLS AND METHOD FOR THE PRODUCTION THEREOF | Aventis Pharma Deutschland GmbH (DE) | 2005-02-09 | — | — | EP | claimed |
| WO-2004089917-A2 | PROCESS FOR RESOLVING 2,4-DIAMINO-3,6-DIHYDRO-1,3,5-TRIAZINES, USEFUL FOR THE TREATMENT OF DISORDERS ASSOCIATED WITH INSULIN RESISTANCE SYNDROME | MERCK PATENT GMBH (DE) | 2004-10-21 | — | — | WO | claimed |
| US-20040030145-A1 | Optically active B-aminoketones, optically active 1,3-amino alcohols and processes for preparing them | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-02-12 | — | — | US | claimed |
| WO-2003093259-A1 | OPTICALLY ACTIVE β-AMINOKETONES, OPTICALLY ACTIVE 1,3-AMINOALCOHOLS AND METHOD FOR THE PRODUCTION THEREOF | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-11-13 | — | — | WO | claimed |
| EP-0420120-B1 | Optically active benzyl alcohol compound and pharmaceutical composition | HOKURIKU PHARMACEUTICAL (JP) | 1994-08-31 | — | — | EP | claimed |
| EP-0420120-A2 | Optically active benzyl alcohol compound and pharmaceutical composition | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1991-04-03 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267104-A1 | E.g., ({[Acetyl({(5R)-3-[4-(1,1-dioxidotetrahydro-2H-thiopyran4-yl)-3-fluorophenyl]-2-oxo-1,3-oxazolidin-5-yl}-methyl)amino]carbonyl}oxymethyl acetate; these compounds have potent activity with excellent oral bioavailability against Gram-positive and Gram-negative bacteria | HDAC3, HDAC1, OGA | PTGS2 2423/4885PTGS1 1704/4885LMNA 4674/4885 |
| US-11999741-B2 | Process for the synthesis of 6-((3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl)-3-(tetrahydropyran-4-yl-7H-imidazo[1,5-a]pyrazin-8-one | CDK8, PRMT8, RPS8 | PTGS2 1686/4885PTGS1 2087/4885LMNA 1751/4885 |
| US-20040030145-A1 | Optically active B-aminoketones, optically active 1,3-amino alcohols and processes for preparing them | ORMDL3, OR10J3, BCAT2 | PTGS2 3604/4885PTGS1 3472/4885LMNA 2390/4885 |
| US-20230122169-A1 | NOVEL METHOD FOR PREPARING (-)-CIBENZOLINE SUCCINATE | SDHA, SDHB, ALDH5A1 | PTGS2 2050/4885PTGS1 2452/4885LMNA 3951/4885 |
| US-11760750-B1 | Process for preparing levoketoconazole | KHK, KYAT3, PLK3 | PTGS2 4662/4885PTGS1 4621/4885LMNA 1990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.