Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAUR | Q03405 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5336924 | 0.98 | PLAUR (0.46) | PLAURALDH1A1TSHRCYP2C19NPC1 | |
| SCHEMBL8967704 | 0.87 | CYP3A4 (0.46) | PLAURALDH1A1TSHRCYP2C19NPC1 | |
| SCHEMBL2693525 | 0.87 | HCAR2 (0.42) | PLAURALDH1A1TSHRCYP2C19LMNA | |
| SCHEMBL28915934 | 0.78 | MAPT (0.55) | ALDH1A1TSHRNPC1GAALMNA | |
| Phenazine SCHEMBL19970688 | 0.78 | MAPT (0.55) | ALDH1A1TSHRNPC1GAALMNA | |
| SCHEMBL2360699 | 0.78 | PLAUR (0.59) | PLAURALDH1A1TSHRRAB9AGAA | |
| SCHEMBL22589760 | 0.77 | PLAUR (0.47) | PLAURALDH1A1TSHRCYP2C19GAA | |
| Hydrochloric Acid SCHEMBL22748626 | 0.76 | PLAUR (0.57) | PLAURALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL9169312 | 0.74 | METAP1 (0.40) | ALDH1A1NPC1RAB9AGAALMNA | |
| SCHEMBL28486850 | 0.73 | ALDH1A1 (0.48) | ALDH1A1TSHRCYP2C19NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023190663-A1 | HIGH-PURITY COMPOUND PRODUCTION METHOD AND PURIFICATION METHOD | 参天製薬株式会社 | 2023-10-05 | — | — | WO | claimed |
| EP-1590355-A1 | NOVEL TRICYCLIC AZEPINE DERIVATIVES, METHOD FOR PRODUCTION THEROF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | LES LABORATOIRES SERVIER (FR) | 2005-11-02 | — | — | EP | claimed |
| WO-2004069843-A1 | NOVEL TRICYCLIC AZEPINE DERIVATIVES, METHOD FOR PRODUCTION THEROF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | LES LABORATOIRES SERVIER (FR) | 2004-08-19 | — | — | WO | claimed |
| EP-0634932-A1 | METHOD FOR REDUCING INTRAOCULAR PRESSURE IN THE MAMMALIAN EYE BY ADMINISTRATION OF MUSCARINIC ANTAGONISTS | ALLERGAN, INC. (US) | 1995-01-25 | — | — | EP | claimed |
| WO-1993018772-A1 | METHOD FOR REDUCING INTRAOCULAR PRESSURE IN THE MAMMALIAN EYE BY ADMINISTRATION OF MUSCARINIC ANTAGONISTS | ALLERGAN, INC. (US) | 1993-09-30 | — | — | WO | claimed |
| EP-0254955-B1 | Substituted pyrido[2,3-b][1,4]benzodiazepin-6-ones, process for their preparation and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1992-05-27 | — | — | EP | claimed |
| EP-0254955-A2 | Substituted pyrido[2,3-b][1,4]benzodiazepin-6-ones, process for their preparation and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1988-02-03 | — | — | EP | claimed |
| JP-1193225-A | — | — | None | — | — | JP | disclosed |
| US-12156868-B2 | Formulations of pilocarpine and brimonidine compounds and related methods | SOMERSET THERAPEUTICS, LLC (US) | 2024-12-03 | — | — | US | disclosed |
| US-11857538-B2 | Stable pilocarpine formulations with modified buffer characteristics and related methods | SOMERSET THERAPEUTICS, LLC (US) | 2024-01-02 | — | — | US | disclosed |
| US-11857539-B2 | Gel ophthalmic formulations of pilocarpine and brimonidine compounds and related methods | SOMERSET THERAPEUTICS, LLC (US) | 2024-01-02 | — | — | US | disclosed |
| WO-2023190653-A1 | STERILIZATION METHOD OF PHARMACEUTICAL PREPARATION AND PACKAGING | 参天製薬株式会社 | 2023-10-05 | — | — | WO | disclosed |
| WO-2023190663-A1 | HIGH-PURITY COMPOUND PRODUCTION METHOD AND PURIFICATION METHOD | 参天製薬株式会社 | 2023-10-05 | — | — | WO | disclosed |
| JP-H01193225-A | ANTIMUSCARINIC AGENT CONTAINING AROMATIC COMPOUND AS ACTIVE COMPONENT | DOMPE FARMACEUT SPA | 1989-08-03 | — | — | JP | disclosed |
| EP-0312895-A2 | Condensed diazepinones, process for their preparation and medicament containing them | Dr. Karl Thomae GmbH (DE) | 1989-04-26 | — | — | EP | disclosed |
| EP-0288201-A1 | Process for the preparation of benzodiazepines | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-10-26 | — | — | EP | disclosed |
| US-4749788-A | Process for the preparation of aryl-pyrido(1,4) benzodiazepines | A. H. ROBINS COMPANY, INCORPORATED (US) | 1988-06-07 | — | — | US | disclosed |
| EP-0254955-A2 | Substituted pyrido[2,3-b][1,4]benzodiazepin-6-ones, process for their preparation and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1988-02-03 | — | — | EP | disclosed |
| EP-0254955-A2 | Substituted pyrido[2,3-b][1,4]benzodiazepin-6-ones, process for their preparation and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1988-02-03 | — | — | EP | disclosed |
| EP-0254955-A2 | Substituted pyrido[2,3-b][1,4]benzodiazepin-6-ones, process for their preparation and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1988-02-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11857538-B2 | Stable pilocarpine formulations with modified buffer characteristics and related methods | PDE4B, PDE6A, PDE10A | PLAUR 1484/4885ALDH1A1 4157/4885TSHR 1719/4885 |
| US-11857539-B2 | Gel ophthalmic formulations of pilocarpine and brimonidine compounds and related methods | PDE6C, PDE6D, PDE6H | PLAUR 2265/4885ALDH1A1 3996/4885TSHR 1850/4885 |
| US-12156868-B2 | Formulations of pilocarpine and brimonidine compounds and related methods | PDE6C, PDE6H, SLC6A11 | PLAUR 2076/4885ALDH1A1 3717/4885TSHR 781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.