Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10435516 | 0.94 | TBXAS1 (0.47) | TBXAS1LMNAALDH1A1SLC22A6MAPT | |
| SCHEMBL1898999 | 0.93 | TBXAS1 (0.50) | TBXAS1LMNAALDH1A1MAPTTSHR | |
| SCHEMBL20659611 | 0.93 | TBXAS1 (0.50) | TBXAS1LMNAALDH1A1MAPTTSHR | |
| SCHEMBL1892347 | 0.93 | TBXAS1 (0.50) | TBXAS1LMNAALDH1A1MAPTTSHR | |
| SCHEMBL1888744 | 0.93 | TBXAS1 (0.50) | TBXAS1LMNAALDH1A1MAPTTSHR | |
| SCHEMBL1889345 | 0.93 | TBXAS1 (0.50) | TBXAS1LMNAALDH1A1MAPTTSHR | |
| SCHEMBL8464719 | 0.93 | TBXAS1 (0.50) | TBXAS1LMNAALDH1A1MAPTTSHR | |
| SCHEMBL420407 | 0.93 | TBXAS1 (0.50) | TBXAS1LMNAALDH1A1MAPTTSHR | |
| SCHEMBL2704416 | 0.88 | CHRM1 (0.39) | TBXAS1LMNAALDH1A1GAA | |
| SCHEMBL4570513 | 0.83 | PAOX (0.32) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218858-B | 2, 6-Diamino-3, 4-dihydropyrimidin-4-one derivatives and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2024-06-18 | — | — | CN | claimed |
| CN-101993421-B | Synthesis and application of blue-fluorescence luminous zinc metal complex | FUJIAN MATTER STRUCTURE | 2014-04-16 | — | — | CN | claimed |
| CN-120153318-A | Photosensitive resin composition, method for producing cured relief pattern using same, and method for producing polyimide film | 旭化成株式会社 | 2025-06-13 | — | — | CN | disclosed |
| CN-112218858-B | 2, 6-Diamino-3, 4-dihydropyrimidin-4-one derivatives and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2024-06-18 | — | — | CN | disclosed |
| EP-4281119-A1 | PRECURSOR MARKER AND RADIOTRACER FOR NUCLEAR-MEDICAL DIAGNOSIS AND THERAPY OF BONE-METASTATIC PROSTATE CANCER | SCV - SpezialChemikalienVertrieb GmbH (DE) | 2023-11-29 | — | — | EP | disclosed |
| EP-3781554-B1 | 2,6-DIAMINO-3,4-DIHYDROPYRIMIDIN-4-ONE DERIVATIVES AND USE THEREOF IN THERAPY | THOMAS HELLEDAYS STIFTELSE FOER MEDICINSK FORSKNING (SE) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022157277-A1 | PRECURSOR MARKER AND RADIOTRACER FOR NUCLEAR-MEDICAL DIAGNOSIS AND THERAPY OF BONE-METASTATIC PROSTATE CANCER | SCV - SpezialChemikalienVertrieb GmbH (DE) | 2022-07-28 | — | — | WO | disclosed |
| CN-110078735-B | Pyrrolopyrimidine compounds having antitumor activity and use thereof | 河北医科大学 | 2022-02-18 | — | — | CN | disclosed |
| EP-3777898-A2 | COMPOUNDS FOR POSITRON EMISSION TOMOGRAPHY | Endocyte, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |
| EP-3533473-A2 | COMPOUNDS FOR POSITRON EMISSION TOMOGRAPHY | Endocyte, Inc. (US) | 2019-09-04 | — | — | EP | disclosed |
| US-20160287731-A1 | Compounds for Positron Emission Tomography | ENDOCYTE, INC | 2016-10-06 | — | — | US | disclosed |
| WO-2015073678-A1 | COMPOUNDS FOR POSITRON EMISSION TOMOGRAPHY | ENDOCYTE, INC. (US) | 2015-05-21 | — | — | WO | disclosed |
| CN-101993421-B | Synthesis and application of blue-fluorescence luminous zinc metal complex | FUJIAN MATTER STRUCTURE | 2014-04-16 | — | — | CN | disclosed |
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |
| CN-101993421-A | Synthesis and application of blue-fluorescence luminous zinc metal complex | FUJIAN INST RES STR MATTER CAS | 2011-03-30 | — | — | CN | disclosed |
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |
| US-4925948-A | CEPHALOSPORIN ANTIBIOTIC CHEMICAL INTERMEDIATES | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| EP-0055465-B1 | 7-ACYLAMINOCEPHALOSPORANIC ACID DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-08-23 | — | — | EP | disclosed |
| US-4596829-A | Pharmaceuticals | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-06-24 | — | — | US | disclosed |
| US-4438113-A | 7-Acylaminocephalosporanic acid derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160287731-A1 | Compounds for Positron Emission Tomography | FOLH1, FOLR2, FOLR1 | TBXAS1 3537/4885HDAC3 3954/4885MAPK1 3440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.