Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 15/20 | 0.58 |
| ▸ | NPY1R | P25929 | 10/20 | 0.58 |
| ▸ | NPY5R | Q15761 | 9/20 | 0.58 |
| ▸ | TFPI | P10646 | 1/20 | 0.57 |
| ▸ | NPY2R | P49146 | 6/20 | 0.54 |
| ▸ | IL23R | Q5VWK5 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16509077 | 0.89 | NPY4R (0.57) | NPY4RNPY1RNPY5RTFPINPY2R | |
| SCHEMBL16509135 | 0.88 | IL23R (0.57) | NPY4RNPY1RNPY5RTFPIIL23R | |
| SCHEMBL16509008 | 0.88 | IL23R (0.57) | NPY4RNPY1RNPY5RTFPIIL23R | |
| SCHEMBL16508128 | 0.84 | NPY4R (0.67) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL16508137 | 0.84 | NPY4R (0.67) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29353517 | 0.84 | TFPI (0.57) | NPY4RNPY1RNPY5RTFPINPY2R | |
| SCHEMBL16508036 | 0.84 | NPY4R (0.70) | NPY4RNPY1RNPY5RTFPINPY2R | |
| SCHEMBL16509090 | 0.83 | TFPI (0.60) | TFPIIL23R | |
| SCHEMBL16507911 | 0.83 | NPY4R (0.65) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL16507904 | 0.83 | NPY4R (0.65) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110301087-A1 | CRF1 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. | 2011-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301087-A1 | CRF1 RECEPTOR COMPOUNDS | CRHR1, CRH, CRHR2 | NPY4R 109/4885NPY1R 47/4885NPY5R 149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.