SCHEMBL16509048

SCHEMBL16509048

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nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TASP1 Q9H6P5 1/20 0.49
▸ NPY4R P50391 12/20 0.42
▸ KISS1R Q969F8 2/20 0.41
▸ NPY1R P25929 8/20 0.40
▸ NPY5R Q15761 8/20 0.40
▸ NPY2R P49146 5/20 0.40
▸ GRIN2D O15399 1/20 0.40
▸ GRIN3B O60391 1/20 0.40
▸ GRIN1 Q05586 1/20 0.40
▸ GRIN2A Q12879 1/20 0.40
▸ GRIN2B Q13224 1/20 0.40
▸ GRIN2C Q14957 1/20 0.40
▸ GRIN3A Q8TCU5 1/20 0.40
▸ TFPI P10646 1/20 0.39
▸ RXFP1 Q9HBX9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16509130 0.87 NPY4R (0.44) NPY4RNPY1RNPY5RNPY2R
SCHEMBL16508601 0.85 NPY4R (0.47) TASP1NPY4RKISS1RNPY1RNPY5R
SCHEMBL16509027 0.84 NPY4R (0.52) NPY4RKISS1RNPY1RNPY5RNPY2R
SCHEMBL30777485 0.81 NPY4R (0.46) TASP1NPY4RNPY1RNPY5RNPY2R
Leupeptin SCHEMBL583830 0.79 NPY4R (0.46) NPY4RKISS1RNPY1RNPY5RNPY2R
Leupeptin SCHEMBL11021602 0.79 NPY4R (0.46) NPY4RKISS1RNPY1RNPY5RNPY2R
Leupeptin SCHEMBL4669504 0.79 NPY4R (0.46) NPY4RKISS1RNPY1RNPY5RNPY2R
Leupeptin SCHEMBL13933715 0.79 NPY4R (0.46) NPY4RKISS1RNPY1RNPY5RNPY2R
SCHEMBL11094153 0.78 SMN1; SMN2 (0.42) NPY4RNPY1RNPY5RNPY2R
Leupeptin SCHEMBL11596919 0.78 NPY4R (0.46) NPY4RKISS1RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110301087-A1 CRF1 RECEPTOR COMPOUNDS ANCHOR THERAPEUTICS, INC. 2011-12-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110301087-A1 CRF1 RECEPTOR COMPOUNDS CRHR1, CRH, CRHR2 TASP1 2780/4885NPY4R 109/4885KISS1R 363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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