Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAC1 | P63000 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12070583 | 0.91 | RAC1 (0.49) | RAC1LMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL14927008 | 0.89 | LMNA (0.43) | LMNANPSR1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL16510761 | 0.80 | RAC1 (0.35) | RAC1LMNANPSR1KDM4EMAPT | |
| SCHEMBL13757363 | 0.78 | SMN1; SMN2 (0.55) | RAC1LMNANPSR1KDM4EMAPT | |
| SCHEMBL16510485 | 0.77 | KDM4E (0.63) | RAC1LMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL147237 | 0.75 | RAC1 (0.68) | RAC1LMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL12072037 | 0.74 | SMN1; SMN2 (0.45) | RAC1LMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL15483493 | 0.73 | SQOR (0.59) | LMNANPSR1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL9986895 | 0.71 | SMN1; SMN2 (0.50) | RAC1LMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL12070505 | 0.71 | RAD52 (0.53) | RAC1LMNAKDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011156626-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-12-15 | — | — | WO | disclosed |