Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29661836 | 0.78 | LMNA (0.44) | LMNATRPA1PTGS1CACNA1CGAA | |
| SCHEMBL19317747 | 0.78 | LMNA (0.44) | LMNATRPA1PTGS1CACNA1CGAA | |
| SCHEMBL6895537 | 0.78 | LMNA (0.44) | LMNATRPA1PTGS1CACNA1CGAA | |
| SCHEMBL3189801 | 0.74 | LMNA (0.41) | LMNATRPA1PTGS1CACNA1CGAA | |
| SCHEMBL1762674 | 0.74 | LMNA (0.58) | LMNATRPA1PTGS1CACNA1CGAA | |
| SCHEMBL25027728 | 0.74 | LMNA (0.41) | LMNATRPA1PTGS1CACNA1CGAA | |
| SCHEMBL10227597 | 0.74 | LMNA (0.52) | LMNATRPA1PTGS1CACNA1CGAA | |
| SCHEMBL1506620 | 0.73 | S1PR1 (0.46) | LMNATRPA1PTGS1CACNA1CGAA | |
| SCHEMBL7115631 | 0.73 | LMNA (0.40) | LMNATRPA1PTGS1CACNA1CGAA | |
| SCHEMBL22618958 | 0.73 | LMNA (0.40) | LMNATRPA1PTGS1CACNA1CGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011152477-A1 | NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2011-12-08 | — | — | WO | disclosed |