Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | FABP3 | P05413 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 4/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25710691 | 0.83 | LMNA (0.36) | LMNATRPA1GABRA1GABRB2PTGS1 | |
| SCHEMBL24868612 | 0.81 | LMNA (0.41) | LMNATRPA1GABRA1GABRB2PTGS1 | |
| SCHEMBL19317747 | 0.80 | LMNA (0.44) | LMNATRPA1PTGS1CACNA1CALOX12 | |
| SCHEMBL778017 | 0.77 | LMNA (0.46) | LMNATRPA1GABRA1GABRB2PTGS1 | |
| SCHEMBL29630154 | 0.77 | LMNA (0.46) | LMNATRPA1GABRA1GABRB2PTGS1 | |
| SCHEMBL10227597 | 0.76 | LMNA (0.52) | LMNATRPA1PTGS1CACNA1CALOX12 | |
| SCHEMBL16511366 | 0.74 | LMNA (0.40) | LMNATRPA1PTGS1CACNA1CALOX12 | |
| SCHEMBL23771856 | 0.74 | RECQL (0.36) | LMNATRPA1GABRA1GABRB2PTGS1 | |
| SCHEMBL22618958 | 0.74 | LMNA (0.40) | LMNATRPA1PTGS1CACNA1CALOX12 | |
| SCHEMBL11063120 | 0.74 | LMNA (0.40) | LMNATRPA1GABRA1GABRB2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230049402-A1 | NOVEL PHENOL COMPOUND OR SALT THEREOF | TAIHO PHARMACEUTICAL CO. LTD. (JP) | 2023-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230049402-A1 | NOVEL PHENOL COMPOUND OR SALT THEREOF | MYB, MLX, EP300 | LMNA 2792/4885TRPA1 1249/4885GABRA1 3937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.