Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12730850 | 0.89 | ADRB3 (0.39) | ADRB3ADRA2BADRA2C | |
| SCHEMBL12777041 | 0.89 | ADRB3 (0.39) | ADRB3ADRA2BADRA2C | |
| SCHEMBL8212674 | 0.87 | ADRB3 (0.34) | ADRB3ADRA2BADRA2C | |
| SCHEMBL8223794 | 0.87 | ADRB3 (0.34) | ADRB3ADRA2BADRA2C | |
| SCHEMBL12844698 | 0.85 | CTSB (0.40) | ADRB3ADRA2BADRA2C | |
| SCHEMBL8006962 | 0.85 | DPP4 (0.34) | ADRB3ADRA2BADRA2C | |
| SCHEMBL2158325 | 0.84 | ADRB3 (0.34) | ADRB3ADRA2BADRA2C | |
| SCHEMBL8380497 | 0.84 | CTSB (0.33) | ADRB3ADRA2BADRA2C | |
| SCHEMBL7873466 | 0.84 | ADRB3 (0.40) | ADRB3ADRA2BADRA2C | |
| SCHEMBL8383007 | 0.83 | CYP3A4 (0.40) | ADRB3ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011156337-A2 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 2011-12-15 | — | — | WO | disclosed |