Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8212674 | 1.00 | ADRB3 (0.34) | ADRB3ADRA2BADRA2C | |
| SCHEMBL11975703 | 0.91 | ADRB3 (0.34) | ADRB3ADRA2BADRA2C | |
| SCHEMBL12730861 | 0.91 | ADRB3 (0.34) | ADRB3ADRA2BADRA2C | |
| SCHEMBL8379129 | 0.88 | ADRB3 (0.36) | ADRB3ADRA2BADRA2C | |
| SCHEMBL8171994 | 0.88 | — | — | |
| SCHEMBL13811481 | 0.88 | ADRB3 (0.39) | ADRB3ADRA2BADRA2C | |
| SCHEMBL8249373 | 0.87 | DPP4 (0.37) | — | |
| SCHEMBL16512401 | 0.87 | ADRB3 (0.38) | ADRB3ADRA2BADRA2C | |
| SCHEMBL8243020 | 0.87 | ADRB3 (0.32) | ADRB3ADRA2BADRA2C | |
| SCHEMBL8185437 | 0.86 | ADRB3 (0.31) | ADRB3ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305695-A2 | Macrocyclic inhibitors of Hepatitis C virus replication | Intermune, Inc. (US) | 2011-04-06 | — | — | EP | disclosed |
| EP-2305696-A2 | Macrocyclic inhibitors of Hepatitis C virus replication | Intermune, Inc. (US) | 2011-04-06 | — | — | EP | disclosed |
| WO-2008022006-A2 | ARYLALKOXYL HEPATITIS C VIRUS PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |