Mandelic Acid

Mandelic Acid

SCHEMBL165161

O=C(O)[C@H](O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 1.00
MAPK1 P28482 1/20 1.00
CES2 O00748 2/20 0.62
CES1 P23141 2/20 0.62
SRC P12931 2/20 0.59
CYP2D6 P10635 1/20 0.59
HPGD P15428 1/20 0.56
L3MBTL1 Q9Y468 2/20 0.48
POLB P06746 1/20 0.48
PKM P14618 1/20 0.48
PTPN1 P18031 1/20 0.48
PTPN7 P35236 1/20 0.48
BLM P54132 1/20 0.48
KMT2A Q03164 1/20 0.48
ESR2 Q92731 1/20 0.48
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
TDP1 Q9NUW8 1/20 0.46
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mandelic Acid SCHEMBL5313046 1.00 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL21647917 1.00 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL1050 1.00 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL29777368 1.00 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL255601 1.00 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL1374278 0.97 LMNA (0.95) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL3934174 0.97 LMNA (0.95) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL9188111 0.97 LMNA (0.95) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL1680817 0.97 LMNA (0.95) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL5000945 0.97 LMNA (0.95) LMNAMAPK1CES2CES1SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2994 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630520-B2 Left-handed bicyclic morpholine and salt thereof, preparation method therefor, pharmaceutical composition, and use INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2026-05-19 US claimed
WO-2026086809-A1 PROCESS FOR PREPARING 3- [ (3AS, 6AR) -5- {5-CHLORO-2- [ (1-METHYL-1H-PYRAZOL-4-YL) AMINO] PYRIMIDIN-4-YL} -3A-METHYL-OCTAHYDROPYRROLO [3, 4-C] PYRROLE-2-YL] -3-OXOPROPIONITRILE BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) 2026-04-30 WO claimed
EP-4688761-A1 (S)-TIANEPTINE AND USE IN TREATING DISORDERS AND CONDITIONS ASSOCIATED WITH PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR Tonix Pharma Limited (IE) 2026-02-11 EP claimed
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
EP-3908582-B1 SOLID FORMS COMPRISING (S)-4-(4-(4-(((2-(2,6-DIOXOPIPERIDIN-3-YL)-1-OXOISOINDOLIN-4-YL)OXY)METHYL) BENZYL)PIPERAZIN-1-YL)-3-FLUOROBENZONITRILE AND SALTS THEREOF, AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME CELGENE CORP (US) 2025-11-12 EP claimed
EP-4626904-A1 MANDELIC ACID SALT OF PALMITOYL LYSYLVALYL-LYSINE DSM IP Assets B.V. (NL) 2025-10-08 EP claimed
US-20250276974-A1 PROCESS FOR PREPARING ZANUBRUTINIB IN AMORPHOUS FORM OLON S.P.A. (IT) 2025-09-04 US claimed
US-20250270361-A1 CHIRAL METAL OXIDE NANOSTRUCTURE, AND METHOD FOR PRODUCING SAME EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION (KR) 2025-08-28 US claimed
CN-115820483-B Gluconobacter oxydans capable of tolerating high-concentration mandelic acid and application thereof 江南大学 2025-06-24 CN claimed
CN-120192277-A Preparation method of etomidate 仁合益康集团有限公司 2025-06-24 CN claimed
CN-1803756-A Process for the preparation of cyclopropyl carboxylic acid esters and derivativesr ASTRAZENECA AB (SE) 2006-07-19 CN claimed
CN-1740156-A Diastereomeric salts of terfenadine MERRELL PHARMA INC (US) 2006-03-01 CN claimed
CN-1431992-A Process for preparation of cyclopropyl carboxylic acid esters and derivatives thereof ASTRAZENECA AB (SE) 2003-07-23 CN claimed
US-20030120105-A1 Process for the preparation of cyclopropyl carboxylic acid esters and derivatives ASTRAZENECA AB (SE) 2003-06-26 US claimed
EP-1015432-B1 SEPARATION OF ENANTIOMERS OF OCTAHYDROISOQUINOLINE B I CHEMICALS INC (US) 2002-05-02 EP claimed
CN-1309121-A Method for resolving alpha- [ 4- (1, 1-dimethylethyl) phenyl ] -4- (hydroxydiphenylmethyl) -1-piperidinebutanol and compounds derived therefrom MERRELL DOW PHARMA (US) 2001-08-22 CN claimed
US-5663354-A Process for preparing enantiomerically pure 6-[(4-chlorophenyl) (1H-1,2,4-triazol-1-yl) methyl]-1-methyl-1H-benzotrizole JANSSEN PHARMACEUTICA, N.V. (BE) 1997-09-02 US claimed
CN-1148382-A Process and diastereomeric salts for optical resolution of racemic alpha- [4- (1, 1-dimethylethyl) phenyl ] -4- (hydroxydiphenylmethyl) -1-piperidinebutanol and compounds derived therefrom MERRELL DOW PHARMA (US) 1997-04-23 CN claimed
EP-0668861-A1 PROCESS FOR PREPARING ENANTIOMERICALLY PURE 6- (4-CHLOROPHENYL)(1H --TRIAZOL-1,2,4-TRIAZOL-1-YL)METHYL]-1-METHYL-1H --BENZOTRIAZOLE JANSSEN PHARMACEUTICA N.V. (BE) 1995-08-30 EP claimed
WO-1994011364-A1 PROCESS FOR PREPARING ENANTIOMERICALLY PURE 6-[(4-CHLOROPHENYL)(1H^_-TRIAZOL-1,2,4-TRIAZOL-1-YL)METHYL]-1-METHYL-1H^_-BENZOTRIAZOLE JANSSEN PHARMACEUTICA N.V. (BE) 1994-05-26 WO claimed