Mandelic Acid

Mandelic Acid

SCHEMBL255601

O=C(O)[C@@H](O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 1.00
MAPK1 P28482 1/20 1.00
CES2 O00748 2/20 0.62
CES1 P23141 2/20 0.62
SRC P12931 2/20 0.59
CYP2D6 P10635 1/20 0.59
HPGD P15428 1/20 0.56
L3MBTL1 Q9Y468 2/20 0.48
POLB P06746 1/20 0.48
PKM P14618 1/20 0.48
PTPN1 P18031 1/20 0.48
PTPN7 P35236 1/20 0.48
BLM P54132 1/20 0.48
KMT2A Q03164 1/20 0.48
ESR2 Q92731 1/20 0.48
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
TDP1 Q9NUW8 1/20 0.46
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mandelic Acid SCHEMBL5313046 1.00 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL165161 1.00 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL21647917 1.00 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL1050 1.00 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL29777368 1.00 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL1374278 0.97 LMNA (0.95) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL3934174 0.97 LMNA (0.95) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL9188111 0.97 LMNA (0.95) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL1680817 0.97 LMNA (0.95) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL5000945 0.97 LMNA (0.95) LMNAMAPK1CES2CES1SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1872 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079744-A Method for resolution of D, L-menthol enantiomer 2026-05-26 CN claimed
CN-122079804-A Production method of high-purity (1R, 2S, 5R) -WS-3 2026-05-26 CN claimed
EP-4265604-B1 OXASPIRO SUBSTITUTED PYRROLOPYRAZOLE DERIVATIVE, INTERMEDIATE THEREOF, AND PREPARATION METHOD THEREFOR SHANGHAI HAIYAN PHARMACEUTICAL TECH CO LTD (CN) 2026-04-01 EP claimed
EP-4688761-A1 (S)-TIANEPTINE AND USE IN TREATING DISORDERS AND CONDITIONS ASSOCIATED WITH PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR Tonix Pharma Limited (IE) 2026-02-11 EP claimed
EP-3568400-B1 PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED 5-AMINO-6H-THIAZOLO[4,5-D]PYRIMIDINE-2,7-DIONE COMPOUNDS HOFFMANN LA ROCHE (CH) 2025-11-19 EP claimed
EP-4626904-A1 MANDELIC ACID SALT OF PALMITOYL LYSYLVALYL-LYSINE DSM IP Assets B.V. (NL) 2025-10-08 EP claimed
US-20250276974-A1 PROCESS FOR PREPARING ZANUBRUTINIB IN AMORPHOUS FORM OLON S.P.A. (IT) 2025-09-04 US claimed
US-20250270361-A1 CHIRAL METAL OXIDE NANOSTRUCTURE, AND METHOD FOR PRODUCING SAME EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION (KR) 2025-08-28 US claimed
CN-119954778-A Synthesis method of lenacipam sodium and series of intermediate compounds thereof 杭州科巢生物科技有限公司 2025-05-09 CN claimed
CN-119275704-B Continuous wave three-dimensional chiral perovskite laser and preparation method thereof 浙江大学 2025-05-02 CN claimed
CN-101389621-A Method for preparing (S) - (-) -N, N-dimethyl-3- (2-thienyl) -3-hydroxypropyl amine serving as intermediate of duloxetine TEVA PHARMA (IL) 2009-03-18 CN claimed
CN-100369897-C Diastereomeric salts of terfenadine MERRELL PHARMA INC (US) 2008-02-20 CN claimed
CN-1740156-A Diastereomeric salts of terfenadine MERRELL PHARMA INC (US) 2006-03-01 CN claimed
US-6756406-B2 ANTIARTHRITIC AGENTS; RHEUMATIC DISEASES; OSTEOARTHRITIS; INHIBITION OF THE INDUCIBLE NITRIC OXIDE SYNTHASE - INDUCED AFTER ACTIVATION OF VASCULAR SMOOTH MUSCLE, MACROPHAGES, ENDOTHELIAL CELLS BY ENOTOXIN AND CYTOKINES PHARMACIA CORPORATION 2004-06-29 US claimed
EP-1317416-A2 2-AMINO-2-ALKYL-4 HEXENOIC AND HEXYNOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS Pharmacia Corporation (US) 2003-06-11 EP claimed
US-20020128510-A1 2-Amino-2-alkyl-4 hexenoic and hexynoic acid derivatives useful as nitric oxide synthase inhibitors PHARMACIA CORPORATION 2002-09-12 US claimed
WO-2002022559-A2 2-AMINO-2-ALKYL-4 HEXENOIC AND HEXYNOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS PHARMACIA CORPORATION (US) 2002-03-21 WO claimed
CN-1309121-A Method for resolving alpha- [ 4- (1, 1-dimethylethyl) phenyl ] -4- (hydroxydiphenylmethyl) -1-piperidinebutanol and compounds derived therefrom MERRELL DOW PHARMA (US) 2001-08-22 CN claimed
CN-1293193-A Preparation of piperidyl amino methyl trifluoro methyl cyclo other compounds PFIZER PRODUCTS CORP (US) 2001-05-02 CN claimed
CN-1148382-A Process and diastereomeric salts for optical resolution of racemic alpha- [4- (1, 1-dimethylethyl) phenyl ] -4- (hydroxydiphenylmethyl) -1-piperidinebutanol and compounds derived therefrom MERRELL DOW PHARMA (US) 1997-04-23 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250276974-A1 PROCESS FOR PREPARING ZANUBRUTINIB IN AMORPHOUS FORM ZYX, ABL2, FYN LMNA 1629/4885MAPK1 781/4885CES2 4598/4885
US-20020128510-A1 2-Amino-2-alkyl-4 hexenoic and hexynoic acid derivatives useful as nitric oxide synthase inhibitors ALOX12, ALOX5, ALOX15 LMNA 3169/4885MAPK1 1215/4885CES2 740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.