Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.61 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 8/20 | 0.61 |
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | JAK2 | O60674 | 3/20 | 0.61 |
| ▸ | JAK1 | P23458 | 2/20 | 0.61 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.60 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.60 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.60 |
| ▸ | CLK2 | P49760 | 1/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.60 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.60 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.60 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.60 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.60 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15764665 | 0.81 | MAOB (0.70) | ROCK2ROCK1RAB9ANPC1JAK2 | |
| SCHEMBL5415932 | 0.81 | MAOB (0.69) | ROCK2ROCK1RAB9ANPC1JAK2 | |
| SCHEMBL8808812 | 0.80 | NPC1 (0.65) | ROCK2ROCK1RAB9ANPC1JAK2 | |
| SCHEMBL5415117 | 0.80 | MAOB (0.80) | ROCK2ROCK1RAB9ANPC1JAK2 | |
| SCHEMBL5707229 | 0.78 | NPC1 (0.72) | ROCK2ROCK1RAB9ANPC1JAK2 | |
| SCHEMBL15764666 | 0.78 | NPC1 (0.81) | ROCK2ROCK1RAB9ANPC1JAK2 | |
| SCHEMBL7261149 | 0.78 | NPC1 (0.68) | ROCK2ROCK1RAB9ANPC1JAK2 | |
| SCHEMBL1163706 | 0.78 | ROCK2 (0.74) | ROCK2ROCK1RAB9ANPC1JAK2 | |
| SCHEMBL15764669 | 0.78 | NPC1 (0.76) | ROCK2ROCK1RAB9ANPC1JAK2 | |
| SCHEMBL5405791 | 0.78 | MAOB (0.65) | ROCK2ROCK1RAB9ANPC1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962322-B2 | Enhancers of induced pluripotent stem cell reprogramming | CITY OF HOPE | 2015-02-24 | — | — | US | disclosed |