Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 13/20 | 0.55 |
| ▸ | PDPK1 | O15530 | 4/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CCND2 | P30279 | 1/20 | 0.38 |
| ▸ | CCND3 | P30281 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15584276 | 0.85 | FLT3 (0.55) | TBK1PDPK1SIRT5FLT3TP53 | |
| SCHEMBL16444175 | 0.81 | TBK1 (0.51) | TBK1PDPK1SIRT5TP53MAPT | |
| SCHEMBL15584658 | 0.81 | TBK1 (0.51) | TBK1PDPK1SIRT5TP53MAPT | |
| SCHEMBL16520165 | 0.80 | TBK1 (0.54) | TBK1 | |
| SCHEMBL15584270 | 0.79 | FLT3 (0.55) | TBK1PDPK1SIRT5FLT3TP53 | |
| SCHEMBL16450117 | 0.78 | FLT3 (0.55) | TBK1PDPK1SIRT5FLT3 | |
| SCHEMBL15585100 | 0.77 | TBK1 (0.48) | TBK1PDPK1SIRT5FLT3TP53 | |
| SCHEMBL16443896 | 0.77 | TBK1 (0.48) | TBK1PDPK1SIRT5FLT3TP53 | |
| SCHEMBL15585844 | 0.77 | TBK1 (0.60) | TBK1PDPK1SIRT5 | |
| SCHEMBL15584511 | 0.77 | TBK1 (0.58) | TBK1PDPK1SIRT5MAPTCDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2840080-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF | Fujifilm Corporation (JP) | 2015-02-25 | — | — | EP | disclosed |