SCHEMBL1652829

SCHEMBL1652829

C=CCP(=O)(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.50
▸ GAA P10253 2/20 0.50
▸ MAPT P10636 2/20 0.50
▸ ALPG P10696 1/20 0.50
▸ ALOX12 P18054 1/20 0.50
▸ NPY1R P25929 1/20 0.50
▸ HTT P42858 1/20 0.50
▸ NPY2R P49146 1/20 0.50
▸ NPSR1 Q6W5P4 1/20 0.50
▸ ALOX15 P16050 1/20 0.48
▸ TSHR P16473 1/20 0.48
▸ USP2 O75604 1/20 0.48
▸ MEN1 O00255 3/20 0.47
▸ KMT2A Q03164 3/20 0.47
▸ LMNA P02545 1/20 0.45
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ CFTR P13569 1/20 0.41
▸ POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3830949 0.82 SMN1; SMN2 (0.49) ALDH1A1GAAMAPTALPGALOX12
SCHEMBL2672564 0.79 ALDH1A1 (0.52) ALDH1A1GAAMAPTALPGALOX12
SCHEMBL9338939 0.78 MAPT (0.33) ALDH1A1GAAMAPTHTTTSHR
SCHEMBL3265122 0.78 ESR1 (0.41) ALDH1A1GAAMAPTALOX15TSHR
SCHEMBL5826314 0.78 CFTR (0.59) ALDH1A1GAAMAPTALPGALOX12
SCHEMBL6634204 0.76 TSHR (0.41) ALDH1A1GAAMAPTALPGALOX12
SCHEMBL5570426 0.75 ALDH1A1 (0.64) ALDH1A1GAAMAPTALPGALOX12
SCHEMBL11323263 0.74 AOX1 (0.42) ALDH1A1HTTALOX15TSHRMEN1
SCHEMBL8147168 0.73 ALDH1A1 (0.56) ALDH1A1GAAMAPTALPGALOX12
SCHEMBL3947699 0.73 ALDH1A1 (0.56) ALDH1A1GAAMAPTALPGALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957540-A Water-based acrylic resin with flame retardant function and preparation method thereof 昆明理工大学 2022-08-30 — — CN claimed
EP-2102311-A1 FLAME RETARDANT COMPOSITION AND METHOD GENERAL ELECTRIC COMPANY (US) 2009-09-23 — — EP claimed
US-7582691-B2 Poly(arylene ether) compositions and articles SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-09-01 — — US claimed
EP-1714977-B1 Synthesis of cyclosporin analogs ISOTECHNIKA INC (CA) 2009-03-11 — — EP claimed
US-7495047-B2 Poly(arylene ether) composition, method, and article AT&T INTELLECTUAL PROPERTY, I, L.P. (US) 2009-02-24 — — US claimed
US-7488766-B2 Polymer composition, method, and article SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-02-10 — — US claimed
EP-1951814-A1 POLY(ARYLENE ETHER) COMPOSITION, METHOD, AND ARTICLE General Electric Company (US) 2008-08-06 — — EP claimed
WO-2008089314-A1 FLAME RETARDANT POLY (ARLENE ETHER) COMPOSITIONS AND ARTICLES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-07-24 — — WO claimed
US-20080171817-A1 POLY(ARYLENE ETHER) COMPOSITIONS AND ARTICLES SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2008-07-17 — — US claimed
EP-1940936-A1 POLYMER COMPOSITION, METHOD, AND ARTICLE General Electric Company (US) 2008-07-09 — — EP claimed
WO-2007044312-A1 POLY(ARYLENE ETHER) COMPOSITION, METHOD, AND ARTICLE GENERAL ELECTRIC COMPANY (US) 2007-04-19 — — WO claimed
WO-2007044294-A1 POLYMER COMPOSITION, METHOD, AND ARTICLE GENERAL ELECTRIC COMPANY (US) 2007-04-19 — — WO claimed
US-20070080330-A1 Flame retardant composition and method CITIBANK, N.A., AS COLLATERAL AGENT 2007-04-12 — — US claimed
US-20070082986-A1 Polymer composition, method, and article SABIC GLOBAL TECHNOLOGIES IP B.V. (NL) 2007-04-12 — — US claimed
US-20070082987-A1 Poly(arylene ether) composition, method, and article SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2007-04-12 — — US claimed
EP-1714977-A2 Synthesis of cyclosporin analogs Isotechnika Inc. (CA) 2006-10-25 — — EP claimed
CN-1571795-A Synthesis of cyclosporin analogs ISOTECHNIKA INC (CA) 2005-01-26 — — CN claimed
EP-1436321-A2 SYNTHESIS OF CYCLOSPORIN ANALOGS Isotechnika Inc. (CA) 2004-07-14 — — EP claimed
US-20030212249-A1 Synthesis of cyclosporin analogs ISOTECHNIKA, INC. (CA) 2003-11-13 — — US claimed
WO-2003033526-A2 SYNTHESIS OF CYCLOSPORIN ANALOGS ISOTECHNIKA INC. (CA) 2003-04-24 — — WO claimed
Send feedback