Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.61 |
| ▸ | TTPA | P49638 | 3/20 | 0.49 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16529640 | 1.00 | MEN1 (0.61) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL16530089 | 1.00 | MEN1 (0.61) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL16530184 | 1.00 | MEN1 (0.61) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL16529641 | 1.00 | MEN1 (0.61) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL16529493 | 1.00 | MEN1 (0.61) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL16529639 | 1.00 | MEN1 (0.61) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL3248521 | 0.85 | PSEN1 (0.62) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL10447273 | 0.81 | ACE2 (0.40) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL21931412 | 0.81 | LMNA (0.55) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL21929591 | 0.81 | LMNA (0.55) | MEN1KMT2APDE4APDE3ATTPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105473567-B | Formation of chromanes and chromenes by using silver (I) or gold (I) salts or complexes | 帝斯曼知识产权资产管理有限公司 | 2020-07-31 | — | — | CN | disclosed |
| EP-3039017-B1 | FORMATION OF CHROMANES AND CHROMENES BY USING SILVER(I) OR GOLD(I) SALTS OR COMPLEXES | DSM IP ASSETS BV (NL) | 2019-01-09 | — | — | EP | disclosed |
| EP-3039017-A1 | FORMATION OF CHROMANES AND CHROMENES BY USING SILVER(I) OR GOLD(I) SALTS OR COMPLEXES | DSM IP Assets B.V. (NL) | 2016-07-06 | — | — | EP | disclosed |
| WO-2015028463-A1 | FORMATION OF CHROMANES AND CHROMENES BY USING SILVER(I) OR GOLD(I) SALTS OR COMPLEXES | DSM IP ASSETS B.V. (NL) | 2015-03-05 | — | — | WO | disclosed |
| EP-2842951-A1 | Formation of chromanes and chromenes by using silver(I) or gold(I) salts or complexes | DSM IP Assets B.V. (NL) | 2015-03-04 | — | — | EP | disclosed |