Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | TTPA | P49638 | 3/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | PNLIP | P16233 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488075 | 0.90 | MEN1 (0.39) | ACE2PDCD1CD274KMT2AMEN1 | |
| SCHEMBL16530185 | 0.81 | MEN1 (0.61) | ACE2PDCD1CD274KMT2AMEN1 | |
| SCHEMBL16529493 | 0.81 | MEN1 (0.61) | ACE2PDCD1CD274KMT2AMEN1 | |
| SCHEMBL16530089 | 0.81 | MEN1 (0.61) | ACE2PDCD1CD274KMT2AMEN1 | |
| SCHEMBL16529641 | 0.81 | MEN1 (0.61) | ACE2PDCD1CD274KMT2AMEN1 | |
| SCHEMBL16530184 | 0.81 | MEN1 (0.61) | ACE2PDCD1CD274KMT2AMEN1 | |
| SCHEMBL16529640 | 0.81 | MEN1 (0.61) | ACE2PDCD1CD274KMT2AMEN1 | |
| SCHEMBL16529639 | 0.81 | MEN1 (0.61) | ACE2PDCD1CD274KMT2AMEN1 | |
| SCHEMBL5998972 | 0.80 | ALDH1A1 (0.42) | KMT2AMEN1PDE4APDE3ATTPA | |
| SCHEMBL9268369 | 0.76 | MEN1 (0.38) | ACE2PDCD1CD274KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369082-A1 | Cardioprotective tocopherol analogs | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-05-23 | — | — | EP | disclosed |