Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1653391 | 0.87 | RAB9A (0.32) | NR1H3ALDH1A1HPGDSMN1; SMN2TSHR | |
| SCHEMBL4521603 | 0.81 | KDM4E (0.36) | NR1H3ALDH1A1HPGDSMN1; SMN2TSHR | |
| SCHEMBL1654169 | 0.80 | KDM4E (0.41) | ALDH1A1HPGDSMN1; SMN2TSHRRAB9A | |
| SCHEMBL1653484 | 0.78 | KDM4E (0.36) | ALDH1A1HPGDSMN1; SMN2TSHRRAB9A | |
| SCHEMBL1653505 | 0.77 | TSHR (0.40) | ALDH1A1HPGDSMN1; SMN2TSHRRAB9A | |
| SCHEMBL13675258 | 0.77 | KDM4E (0.37) | NR1H3ALDH1A1HPGDSMN1; SMN2TSHR | |
| SCHEMBL1654287 | 0.77 | KDM4E (0.39) | NR1H3ALDH1A1HPGDSMN1; SMN2TSHR | |
| SCHEMBL1654156 | 0.76 | MAPT (0.33) | NR1H3ALDH1A1HPGDSMN1; SMN2TSHR | |
| SCHEMBL12784632 | 0.76 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL9073033 | 0.76 | ALDH1A1 (0.34) | NR1H3ALDH1A1HPGDSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308839-A1 | Fused heterocyclic compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-04-13 | — | — | EP | disclosed |