SCHEMBL16536614

SCHEMBL16536614

C=Cc1ccccc1CCCO[Si](C)(OC)OC

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.30
THRB P10828 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16538048 0.91 ALDH1A1 (0.32) ALDH1A1
SCHEMBL16537135 0.88 THRA (0.30) THRATHRBALDH1A1
SCHEMBL16537886 0.87 THRA (0.32) THRATHRB
SCHEMBL16536531 0.87 THRA (0.31) THRATHRBALDH1A1
SCHEMBL16537869 0.85 THRA (0.31) THRATHRB
SCHEMBL16537411 0.84 THRA (0.32) THRATHRB
SCHEMBL16536615 0.83 THRA (0.32) THRATHRB
SCHEMBL16537652 0.82 THRA (0.32) THRATHRB
SCHEMBL16536920 0.81 BACE1 (0.34) ALDH1A1
SCHEMBL16536298 0.81 THRA (0.32) THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9266981-B2 Conjugated diene random copolymer having alkoxysilane unit KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2016-02-23 US disclosed
US-20150065639-A1 CONJUGATED DIENE RANDOM COPOLYMER HAVING ALKOXYSILANE UNIT KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2015-03-05 US disclosed