SCHEMBL16536719

SCHEMBL16536719

C=C(C)C(=O)OC(CCCC)[SiH2]C(C)(OC)OC

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
CA2 P00918 3/20 0.35
CA1 P00915 2/20 0.35
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16535970 0.91 ALDH1A1 (0.37) TSHRALDH1A1
SCHEMBL16537642 0.87 TSHR (0.36) TSHRCA2CA1MAPK1
SCHEMBL16537955 0.85 ALDH1A1 (0.35) TSHRALDH1A1
SCHEMBL16537846 0.84 TSHR (0.36) TSHRCA2CA1ALDH1A1
SCHEMBL16537904 0.80 TSHR (0.42) TSHRCA2CA1MAPK1
SCHEMBL16537588 0.78 THRB (0.33) TSHRALDH1A1
SCHEMBL16537378 0.78 TSHR (0.36) TSHR
SCHEMBL16537218 0.77 TSHR (0.39) TSHRCA2CA1ALDH1A1
SCHEMBL28352185 0.76 TSHR (0.40) TSHRALDH1A1
SCHEMBL16537190 0.75 ALDH1A1 (0.36) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9266981-B2 Conjugated diene random copolymer having alkoxysilane unit KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2016-02-23 US disclosed
US-20150065639-A1 CONJUGATED DIENE RANDOM COPOLYMER HAVING ALKOXYSILANE UNIT KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2015-03-05 US disclosed