Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TNFRSF1A | P19438 | 4/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16538756 | 1.00 | RAB9A (0.54) | RAB9AMAPTNPC1ALDH1A1KDM4E | |
| SCHEMBL16538963 | 0.90 | TNFRSF1A (0.55) | RAB9AMAPTNPC1ALDH1A1KDM4E | |
| SCHEMBL16538966 | 0.90 | TNFRSF1A (0.55) | RAB9AMAPTNPC1ALDH1A1KDM4E | |
| SCHEMBL16539259 | 0.90 | TNFRSF1A (0.56) | RAB9AMAPTNPC1ALDH1A1KDM4E | |
| SCHEMBL16539252 | 0.90 | TNFRSF1A (0.56) | RAB9AMAPTNPC1ALDH1A1KDM4E | |
| SCHEMBL16547632 | 0.88 | RAB9A (0.56) | RAB9AMAPTNPC1ALDH1A1KDM4E | |
| SCHEMBL17924203 | 0.88 | RAB9A (0.56) | RAB9AMAPTNPC1ALDH1A1KDM4E | |
| SCHEMBL17930390 | 0.87 | RAB9A (0.49) | RAB9AMAPTNPC1ALDH1A1KDM4E | |
| SCHEMBL16539248 | 0.86 | MAPT (0.56) | RAB9AMAPTNPC1ALDH1A1KDM4E | |
| SCHEMBL16539243 | 0.86 | MAPT (0.56) | RAB9AMAPTNPC1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3039013-A1 | PYRAZOLOCHALCONES AS POTENTIAL ANTICANCER AGENTS | Council of Scientific and Industrial Research (IN) | 2016-07-06 | — | — | EP | claimed |
| WO-2015029051-A1 | PYRAZOLOCHALCONES AS POTENTIAL ANTICANCER AGENTS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-03-05 | — | — | WO | claimed |
| EP-3039013-B1 | PYRAZOLOCHALCONES AS POTENTIAL ANTICANCER AGENTS | COUNCIL SCIENT IND RES (IN) | 2018-09-12 | — | — | EP | disclosed |
| US-9604933-B2 | Pyrazolochalcones as potential anticancer agents | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-03-28 | — | — | US | disclosed |
| US-20160207888-A1 | PYRAZOLOCHALCONES AS POTENTIAL ANTICANCER AGENTS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-07-21 | — | — | US | disclosed |
| EP-3039013-A1 | PYRAZOLOCHALCONES AS POTENTIAL ANTICANCER AGENTS | Council of Scientific and Industrial Research (IN) | 2016-07-06 | — | — | EP | disclosed |
| WO-2015029051-A1 | PYRAZOLOCHALCONES AS POTENTIAL ANTICANCER AGENTS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160207888-A1 | PYRAZOLOCHALCONES AS POTENTIAL ANTICANCER AGENTS | HCCS, CCNE2, FOXO3 | RAB9A 3238/4885MAPT 4760/4885NPC1 2589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.