SCHEMBL16539705

SCHEMBL16539705

C#CCOc1ccccc1C1CC(c2csc(C3CCN(C(=O)CC(=O)OCC)CC3)n2)=NO1

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FAAH O00519 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15735550 0.89 FAAH (0.57) FAAH
SCHEMBL30105771 0.89 FAAH (0.57) FAAH
SCHEMBL30027249 0.89 FAAH (0.57) FAAH
SCHEMBL16538923 0.87 FAAH (0.53) FAAH
SCHEMBL16539103 0.87 FAAH (0.57) FAAH
SCHEMBL29654949 0.86 FAAH (0.51) FAAH
SCHEMBL15735552 0.81 FAAH (0.49) FAAH
SCHEMBL16654736 0.81 FAAH (0.49) FAAH
SCHEMBL2455520 0.81 FAAH (0.49) FAAH
SCHEMBL29371080 0.81 FAAH (0.49) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9924721-B2 Malonic ester derivatives of heteroarylpiperidines and -piperazines as fungicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-03-27 US disclosed
US-20160198713-A1 Malonic ester derivatives of heteroarylpiperidines and -piperazines as fungicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-07-14 US disclosed
EP-3039023-A1 MALONIC ESTER DERIVATIVES OF HETEROARYLPIPERIDINES AND -PIPERAZINES AS FUNGICIDES Bayer CropScience Aktiengesellschaft (DE) 2016-07-06 EP disclosed
WO-2015028457-A1 MALONIC ESTER DERIVATIVES OF HETEROARYLPIPERIDINES AND -PIPERAZINES AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2015-03-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160198713-A1 Malonic ester derivatives of heteroarylpiperidines and -piperazines as fungicides ME1, CYP1A1, CYP1A2 FAAH 3772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.