Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKBIA | P25963 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1653391 | 0.83 | RAB9A (0.32) | ALDH1A1GAAMEN1HPGDKMT2A | |
| SCHEMBL1654853 | 0.82 | NFKBIA (0.45) | NFKBIARELAGLO1BRD4ALDH1A1 | |
| SCHEMBL1653200 | 0.81 | NFKBIA (0.43) | NFKBIARELAGLO1BRD4ALDH1A1 | |
| SCHEMBL1654477 | 0.81 | NFKBIA (0.47) | NFKBIARELAGLO1BRD4ALDH1A1 | |
| SCHEMBL1653158 | 0.80 | ALDH1A1 (0.45) | NFKBIARELAGLO1BRD4ALDH1A1 | |
| SCHEMBL1653159 | 0.80 | NFKBIA (0.45) | NFKBIARELAGLO1BRD4ALDH1A1 | |
| SCHEMBL13672592 | 0.79 | KMT2A (0.46) | ALDH1A1MEN1KMT2AHSD17B10NPC1 | |
| Acetic Acid SCHEMBL1654444 | 0.78 | NFKBIA (0.49) | NFKBIARELAGLO1ALDH1A1GAA | |
| SCHEMBL13675077 | 0.77 | NFKBIA (0.46) | NFKBIARELAGLO1BRD4ALDH1A1 | |
| SCHEMBL13675005 | 0.77 | NFKBIA (0.43) | NFKBIARELAGLO1BRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308839-A1 | Fused heterocyclic compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-04-13 | — | — | EP | disclosed |