Fluoride

Fluoride

SCHEMBL634375

F.c1ccc(CNCc2ccccc2)cc1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.74
KMT2A Q03164 1/20 0.74
TDP1 Q9NUW8 1/20 0.74
MAOA P21397 1/20 0.64
MAPT P10636 3/20 0.61
CHRM2 P08172 1/20 0.61
GAA P10253 1/20 0.61
PKM P14618 1/20 0.58
BCHE P06276 1/20 0.58
IDO1 P14902 2/20 0.57
THRB P10828 1/20 0.57
ADH1B P00325 1/20 0.56
ADH1C P00326 1/20 0.56
ADH1A P07327 1/20 0.56
ADH7 P40394 1/20 0.56
SIGMAR1 Q99720 3/20 0.56
CYP3A4 P08684 2/20 0.55
KDM4E B2RXH2 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5799878 0.97 MEN1 (0.78) MEN1KMT2ATDP1MAOAMAPT
SCHEMBL1654 0.97 MEN1 (0.78) MEN1KMT2ATDP1MAOAMAPT
Benzene SCHEMBL11697595 0.97 MEN1 (0.78) MEN1KMT2ATDP1MAOAMAPT
Ammonia Solution, Strong SCHEMBL2064651 0.94 MEN1 (0.74) MEN1KMT2ATDP1MAOAMAPT
SCHEMBL3990993 0.94 MEN1 (0.74) MEN1KMT2ATDP1MAOAMAPT
Water SCHEMBL11666905 0.94 MEN1 (0.74) MEN1KMT2ATDP1MAOAMAPT
Hydrochloric Acid SCHEMBL1862144 0.94 MEN1 (0.74) MEN1KMT2ATDP1MAOAMAPT
Bromide SCHEMBL998627 0.94 MEN1 (0.74) MEN1KMT2ATDP1MAOAMAPT
SCHEMBL21550054 0.94 MEN1 (0.74) MEN1KMT2ATDP1MAOAMAPT
SCHEMBL30223761 0.94 MEN1 (0.74) MEN1KMT2ATDP1MAOAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2302000-B1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORP (JP) 2016-11-16 EP disclosed
US-9051501-B2 Curable composition and catalyst composition KANEKA CORPORATION (JP) 2015-06-09 US disclosed
EP-2088173-B1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORP (JP) 2012-02-22 EP disclosed
EP-2302000-A1 Curable composition and catalyst composition KANEKA CORPORATION (JP) 2011-03-30 EP disclosed
US-20100041810-A1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORPORATION (JP) 2010-02-18 US disclosed
EP-2088173-A1 CURABLE COMPOSITION AND CATALYST COMPOSITION Kaneka Corporation (JP) 2009-08-12 EP disclosed