Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 6/20 | 0.55 |
| ▸ | TUBB | P07437 | 6/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.55 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.55 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.55 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.55 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.55 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.55 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.55 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16542035 | 0.91 | TUBB4A (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16542015 | 0.87 | MAOB (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL15957799 | 0.84 | CA12 (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16542013 | 0.82 | TUBB1 (0.57) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL15957798 | 0.81 | LTA4H (0.57) | MAPTMAOBMEN1KMT2AESR2 | |
| SCHEMBL12474487 | 0.81 | TUBB4A (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16542011 | 0.81 | TUBB1 (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1918749 | 0.80 | MAOB (0.61) | CYP3A4MAPTMAOBMEN1KMT2A | |
| SCHEMBL16542031 | 0.78 | MAOB (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12474512 | 0.75 | TUBB4A (0.49) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536726-B1 | DIARYL ETHER LINKED PYRROLO [2,1-C][1,4]BENZODIAZEPINE HYBRIDS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2015-03-04 | — | — | EP | disclosed |