SCHEMBL1654460

SCHEMBL1654460

CCc1cc(CN)ccn1

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ LOXL2 Q9Y4K0 13/20 0.55
▸ LOX P28300 5/20 0.55
▸ LOXL3 P58215 1/20 0.55
▸ CYP1A2 P05177 1/20 0.52
▸ POLB P06746 1/20 0.52
▸ NOS3 P29474 1/20 0.50
▸ NOS1 P29475 1/20 0.50
▸ NOS2 P35228 1/20 0.50
▸ ROCK1 Q13464 1/20 0.43
▸ PRKCI P41743 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL218290 0.84 NOS3 (0.61) LOXL2LOXCYP1A2POLBNOS3
SCHEMBL4107151 0.84 LOXL2 (0.61) LOXL2LOXLOXL3NOS3NOS1
SCHEMBL15200880 0.83 NOS3 (0.61) LOXL2LOXLOXL3CYP1A2POLB
SCHEMBL11563922 0.82 NOS3 (0.59) LOXL2LOXCYP1A2POLBNOS3
Hydrochloric Acid SCHEMBL5013442 0.82 LOXL2 (0.59) LOXL2LOXLOXL3NOS3NOS1
SCHEMBL9817617 0.78 LOXL2 (0.55) LOXL2LOXLOXL3ROCK1
Dimethylamine SCHEMBL7744073 0.78 NOS3 (0.55) CYP1A2POLBNOS3NOS1NOS2
SCHEMBL16775566 0.78 CYP1A2 (0.47) LOXL2LOXLOXL3CYP1A2POLB
SCHEMBL2932292 0.78 POLB (0.47) LOXL2LOXCYP1A2POLBNOS3
SCHEMBL2935815 0.78 RECQL (0.55) CYP1A2POLBNOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107759509-A A kind of synthetic method of tropicamide 上海泰坦科技股份有限公司 2018-03-06 — — CN claimed
CN-106554305-A A kind of label, its preparation method, labeling method and application 上海医药临床研究中心 2017-04-05 — — CN claimed
US-20250313561-A1 NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) RYVU THERAPEUTICS S A (PL) 2025-10-09 — — US disclosed
US-12344606-B2 Next-generation modulators of stimulator of interferon genes (STING) Ryvu Therapeutics S.A. (PL) 2025-07-01 — — US disclosed
EP-3983078-B1 NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) RYVU THERAPEUTICS S A (PL) 2023-11-15 — — EP disclosed
EP-3983078-B1 NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) RYVU THERAPEUTICS S A (PL) 2023-11-15 — — EP disclosed
CN-112592312-B Preparation method of tropicamide 无锡济煜山禾药业股份有限公司 2022-10-28 — — CN disclosed
US-20220251082-A1 NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) Ryvu Therapeutics S.A. (PL) 2022-08-11 — — US disclosed
WO-2022145982-A1 TRANSITION METAL COMPLEX CONTAINING TETRADENTATE NITROGEN DONOR LIGAND AND ELECTROCHEMICAL BIOSENSOR COMPRISING SAME 주식회사 아이센스 2022-07-07 — — WO disclosed
EP-3983078-A1 NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) Ryvu Therapeutics S.A. (PL) 2022-04-20 — — EP disclosed
CN-112592312-A Preparation method of tropicamide 无锡济煜山禾药业股份有限公司 2021-04-02 — — CN disclosed
WO-2004007457-A2 SUBSTITUTED BENZYLAMINE DERIVATIVES AND METHODS OF USE AMGEN INC. (US) 2004-01-22 — — WO disclosed
WO-2004007458-A1 SUBSTITUTED 2-ALKYLAMINE NICOTINIC AMIDE DERIVATIVES AND USE THERE OF AMGEN INC. (US) 2004-01-22 — — WO disclosed
WO-2004007481-A2 SUBSTITUTED AMINE DERIVATIVES AND METHODS OF USE IN THE TREATMENT OF ANGIOGENESIS RELATES DISORDERS AMGEN INC. (US) 2004-01-22 — — WO disclosed
WO-2004005279-A2 SUBSTITUTED ANTHRANILIC AMIDE DERIVATIVES AND METHODS OF USE AMGEN INC. (US) 2004-01-15 — — WO disclosed
EP-1358184-A1 SUBSTITUTED ALKYLAMINE DERIVATIVES AND METHODS OF USE Amgen Inc. (US) 2003-11-05 — — EP disclosed
WO-2002068406-A2 SUBSTITUTED AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF ANGIOGENESIS AMGEN INC. (US) 2002-09-06 — — WO disclosed
WO-2002066470-A1 SUBSTITUTED ALKYLAMINE DERIVATIVES AND METHODS OF USE AMGEN INC. (US) 2002-08-29 — — WO disclosed
EP-1056749-A1 NOVEL TRIAZOLO(4,5-d)PYRIMIDINE COMPOUNDS AstraZeneca UK Limited (GB) 2000-12-06 — — EP disclosed
WO-1999041254-A1 NOVEL TRIAZOLO(4,5-d)PYRIMIDINE COMPOUNDS ASTRAZENECA UK LIMITED (GB) 1999-08-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220251082-A1 NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) STING1, IRF3, CGAS LOXL2 1831/4885LOX 2507/4885LOXL3 1749/4885
US-12344606-B2 Next-generation modulators of stimulator of interferon genes (STING) STING1, IRF3, CGAS LOXL2 1831/4885LOX 2507/4885LOXL3 1749/4885
US-20250313561-A1 NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) STING1, IRF3, CGAS LOXL2 1831/4885LOX 2507/4885LOXL3 1749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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