SCHEMBL165447

SCHEMBL165447

CCCCCCCC/C=C\CCCCCCCC(C)(C)N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 6/20 0.50
TRPV1 Q8NER1 1/20 0.50
SOAT1 P35610 2/20 0.48
CYP1A2 P05177 2/20 0.48
CYP2C19 P33261 2/20 0.48
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
TP53 P04637 1/20 0.48
CYP3A4 P08684 1/20 0.48
KDM4E B2RXH2 2/20 0.44
TERT O14746 3/20 0.44
MAPT P10636 2/20 0.44
BLM P54132 2/20 0.44
HSD17B10 Q99714 2/20 0.44
FABP4 P15090 2/20 0.44
PTPN1 P18031 2/20 0.44
PPARG P37231 2/20 0.44
PPARD Q03181 2/20 0.44
PPARA Q07869 2/20 0.44
GMNN O75496 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9202958 1.00 FAAH (0.50) FAAHTRPV1SOAT1CYP1A2CYP2C19
SCHEMBL9211940 1.00 FAAH (0.50) FAAHTRPV1SOAT1CYP1A2CYP2C19
SCHEMBL9211167 1.00 FAAH (0.50) FAAHTRPV1SOAT1CYP1A2CYP2C19
SCHEMBL9210560 1.00 FAAH (0.50) FAAHTRPV1SOAT1CYP1A2CYP2C19
Hydrochloric Acid SCHEMBL9484019 0.98 FAAH (0.48) FAAHTRPV1SOAT1CYP1A2CYP2C19
Ammonia Solution, Strong SCHEMBL21683086 0.98 FAAH (0.48) FAAHTRPV1SOAT1CYP1A2CYP2C19
Hydrochloric Acid SCHEMBL11151898 0.98 FAAH (0.48) FAAHTRPV1SOAT1CYP1A2CYP2C19
SCHEMBL9207284 0.96 FAAH (0.45) FAAHTRPV1SOAT1CYP1A2CYP2C19
SCHEMBL9206537 0.96 FAAH (0.45) FAAHTRPV1SOAT1CYP1A2CYP2C19
SCHEMBL9208702 0.96 FAAH (0.45) FAAHTRPV1SOAT1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 534 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180291137-A1 POLYESTER POLYOL-CONTAINING POLYURETHANE SYSTEMS HAVING IMPROVED HYDROLYTIC STABILITY EVONIK OPERATIONS GMBH (DE) 2018-10-11 US claimed
US-8637584-B2 Polyester polyol-containing polyurethane systems having improved hydrolytic stability AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-01-28 US claimed
US-8361941-B2 Antiwear angent and lubricating compositions thereof THE LUBRIZOL CORPORATION (US) 2013-01-29 US claimed
EP-1125170-B1 TONERS CONTAINING CHARGEABLE MODIFIED PIGMENTS CABOT CORP (US) 2012-06-20 EP claimed
EP-1995262-B1 Polyester polyol-containing polyurethane systems having improved hydrolytic stability AIR PROD & CHEM (US) 2011-10-26 EP claimed
US-20110237472-A1 Antiwear Angent and Lubricating Compositions Thereof THE LUBRIZOL CORPORATION (US) 2011-09-29 US claimed
US-20100016188-A1 Antiwear Agent and Lubricating Compositions Thereof THE LUBRIZOL CORPORATION (US) 2010-01-21 US claimed
US-20080293841-A1 Polyester Polyol-Containing Polyurethane Systems Having Improved Hydrolytic Stability AIR PRODUCTS AND CHEMICALS, INC. (US) 2008-11-27 US claimed
EP-1995262-A1 Polyester polyol-containing polyurethane systems having improved hydrolytic stability Air Products and Chemicals, Inc. (US) 2008-11-26 EP claimed
EP-1484172-B1 Hose construction containing fluoroelastomer composition and fluoroplastic barrier GOODYEAR TIRE & RUBBER (US) 2008-07-09 EP claimed
US-6218067-B1 BLEND OF POLYMER PARTICLES AND REACTION PRODUCT OF PIGMENT CABOT CORPORATION 2001-04-17 US claimed
WO-2000028386-A1 TONERS CONTAINING CHARGEABLE MODIFIED PIGMENTS CABOT CORPORATION (US) 2000-05-18 WO claimed
EP-0562639-B1 Shampoo compositions and suspending agent therefor CURTIS HELENE IND INC (US) 1997-10-29 EP claimed
EP-0303713-B2 PERCUTANEOUS ABSORPTION PROMOTER AND DERMATOLOGIC PREPARATION FOR EXTERNAL USE SHISEIDO CO LTD (JP) 1997-07-30 EP claimed
EP-0562637-B1 Opacifier for water-based compositions CURTIS HELENE IND INC (US) 1997-05-28 EP claimed
US-5077040-A Mixture of water insoluble amino compound, metal salt, and ester HELENE CURTIS, INC. (US) 1991-12-31 US claimed
EP-0455185-A2 Hair-treating microemulsion composition and method of preparing and using the same HELENE CURTIS, INC. (US) 1991-11-06 EP claimed
US-4960588-A WATER INSOLUBLE PRIMARY OR SECONDARY AMINE,IONIZING METAL SALT CARRIER; SHAMPOO, HAIR SPRAY; SOFTNESS, GLOSS HELENE CURTIS, INC. (US) 1990-10-02 US claimed
EP-0369356-A2 Hair treatment compositions to impart durable hair set retention properties Helene Curtis Industries, Inc. (US) 1990-05-23 EP claimed
US-4883912-A Process for the recovery of acetic acid DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1989-11-28 US claimed